L716-0327 Screening compound: 4-({3-[(4-chlorophenyl)sulfanyl]pyrazin-2-yl}oxy)-N-[2-(4-methylpiperazin-1-yl)ethyl]benzamide

L716-0327 Screening compound: 4-({3-[(4-chlorophenyl)sulfanyl]pyrazin-2-yl}oxy)-N-[2-(4-methylpiperazin-1-yl)ethyl]benzamide
L716-0327 Screening compound: 4-({3-[(4-chlorophenyl)sulfanyl]pyrazin-2-yl}oxy)-N-[2-(4-methylpiperazin-1-yl)ethyl]benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L716-0327
4-({3-[(4-chlorophenyl)sulfanyl]pyrazin-2-yl}oxy)-N-[2-(4-methylpiperazin-1-yl)ethyl]benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L716-0327

Molecular Formula

C24H26ClN5O2S (C24 H26 ClN5 O2 S)

Compound Name

4-({3-[(4-chlorophenyl)sulfanyl]pyrazin-2-yl}oxy)-N-[2-(4-methylpiperazin-1-yl)ethyl]benzamide

IUPAC name

4-({3-[(4-chlorophenyl)sulfanyl]pyrazin-2-yl}oxy)-N-[2-(4-methylpiperazin-1-yl)ethyl]benzamide

SMILES

CN1CCN(CCNC(c(cc2)ccc2Oc2nccnc2Sc(cc2)ccc2Cl)=O)CC1

InChI

InChI=1S/C24H26ClN5O2S/c1-29-14-16-30(17-15-29)13-12-26-22(31)18-2-6-20(7-3-18)32-23-24(28-11-10-27-23)33-21-8-4-19(25)5-9-21/h2-11H,12-17H2,1H3,(H,26,31)

InChI Key

DULHVIFFRCQTGS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15133800

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

484.02

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.708

Distribution Coefficient, logD

3.041

Water Solubility, LogSw

-4.36

Polar Surface Area

57.413

Acid Dissociation Constant (pKa)

12.79

Base Dissociation Constant (pKb)

7.96

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.20

L716-0327 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L716-0327 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L716-0327?
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What is the minimum amount of L716-0327 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L716-0327
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L716-0327
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L716-0327 available by request