L718-0595 Screening compound: 3-(1-methanesulfonyl-2,3-dihydro-1H-indol-5-yl)-1-[2-(trifluoromethyl)phenyl]urea

L718-0595 Screening compound: 3-(1-methanesulfonyl-2,3-dihydro-1H-indol-5-yl)-1-[2-(trifluoromethyl)phenyl]urea
L718-0595 Screening compound: 3-(1-methanesulfonyl-2,3-dihydro-1H-indol-5-yl)-1-[2-(trifluoromethyl)phenyl]urea alternative view

Chemical Structure Depiction of ChemDiv screening compound L718-0595
3-(1-methanesulfonyl-2,3-dihydro-1H-indol-5-yl)-1-[2-(trifluoromethyl)phenyl]urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L718-0595

Molecular Formula

C17H16F3N3O3S (C17 H16 F3 N3 O3 S)

Compound Name

3-(1-methanesulfonyl-2,3-dihydro-1H-indol-5-yl)-1-[2-(trifluoromethyl)phenyl]urea

IUPAC name

3-(1-methanesulfonyl-23-dihydro-1H-indol-5-yl)-1-[2-(trifluoromethyl)phenyl]urea

SMILES

CS(N(CC1)c(cc2)c1cc2NC(Nc1c(C(F)(F)F)cccc1)=O)(=O)=O

InChI

InChI=1S/C17H16F3N3O3S/c1-27(25,26)23-9-8-11-10-12(6-7-15(11)23)21-16(24)22-14-5-3-2-4-13(14)17(18,19)20/h2-7,10H,8-9H2,1H3,(H2,21,22,24)

InChI Key

USCBMROWHHYMNI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15133985

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

399.39

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.334

Distribution Coefficient, logD

3.334

Water Solubility, LogSw

-3.83

Polar Surface Area

63.126

Acid Dissociation Constant (pKa)

12.71

Base Dissociation Constant (pKb)

1.57

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.50

L718-0595 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with L718-0595 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L718-0595?
Check Price and Availability of L718-0595, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L718-0595 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L718-0595
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L718-0595
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L718-0595 available by request