L719-1643 Screening compound: 4-[4-(2-methylphenyl)piperazine-1-carbonyl]-2-(pyrrolidin-1-yl)pyrimidine

L719-1643 Screening compound: 4-[4-(2-methylphenyl)piperazine-1-carbonyl]-2-(pyrrolidin-1-yl)pyrimidine
L719-1643 Screening compound: 4-[4-(2-methylphenyl)piperazine-1-carbonyl]-2-(pyrrolidin-1-yl)pyrimidine alternative view

Chemical Structure Depiction of ChemDiv screening compound L719-1643
4-[4-(2-methylphenyl)piperazine-1-carbonyl]-2-(pyrrolidin-1-yl)pyrimidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L719-1643

Molecular Formula

C20H25N5O (C20 H25 N5 O)

Compound Name

4-[4-(2-methylphenyl)piperazine-1-carbonyl]-2-(pyrrolidin-1-yl)pyrimidine

IUPAC name

4-[4-(2-methylphenyl)piperazine-1-carbonyl]-2-(pyrrolidin-1-yl)pyrimidine

SMILES

Cc(cccc1)c1N(CC1)CCN1C(c1nc(N2CCCC2)ncc1)=O

InChI

InChI=1S/C20H25N5O/c1-16-6-2-3-7-18(16)23-12-14-24(15-13-23)19(26)17-8-9-21-20(22-17)25-10-4-5-11-25/h2-3,6-9H,4-5,10-15H2,1H3

InChI Key

MDDMAVJNOYDDCI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27472996

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

351.45

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.441

Distribution Coefficient, logD

3.441

Water Solubility, LogSw

-3.50

Polar Surface Area

41.595

Acid Dissociation Constant (pKa)

19.71

Base Dissociation Constant (pKb)

2.68

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

45.00

L719-1643 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

SmartTM Library (51161 compounds)

Soluble Diversity Library (15920 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L719-1643 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L719-1643?
Check Price and Availability of L719-1643, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L719-1643 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L719-1643
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L719-1643
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L719-1643 available by request