L722-0234 Screening compound: N~3~-(2-fluorobenzyl)-6-(isobutyrylamino)-3-chromanecarboxamide

L722-0234 Screening compound: N~3~-(2-fluorobenzyl)-6-(isobutyrylamino)-3-chromanecarboxamide
L722-0234 Screening compound: N~3~-(2-fluorobenzyl)-6-(isobutyrylamino)-3-chromanecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L722-0234
N~3~-(2-fluorobenzyl)-6-(isobutyrylamino)-3-chromanecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L722-0234

Molecular Formula

C21H23FN2O3 (C21 H23 FN2 O3)

Compound Name

N~3~-(2-fluorobenzyl)-6-(isobutyrylamino)-3-chromanecarboxamide

IUPAC name

N-[(2-fluorophenyl)methyl]-6-(2-methylpropanamido)-34-dihydro-2H-1-benzopyran-3-carboxamide

SMILES

CC(C)C(Nc(cc1)cc(C2)c1OCC2C(NCc(cccc1)c1F)=O)=O

InChI

InChI=1S/C21H23FN2O3/c1-13(2)20(25)24-17-7-8-19-15(10-17)9-16(12-27-19)21(26)23-11-14-5-3-4-6-18(14)22/h3-8,10,13,16H,9,11-12H2,1-2H3,(H,23,26)(H,24,25)/t16-/m0/s1

InChI Key

RRWRPKDNMVUDHI-INIZCTEOSA-N

MDL Number (MFCD)

MFCD27473132

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

370.42

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.403

Distribution Coefficient, logD

3.403

Water Solubility, LogSw

-3.49

Polar Surface Area

56.384

Acid Dissociation Constant (pKa)

11.95

Base Dissociation Constant (pKb)

1.43

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

33.33

L722-0234 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L722-0234 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L722-0234?
Check Price and Availability of L722-0234, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L722-0234 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L722-0234
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L722-0234
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L722-0234 available by request