L728-0211 Screening compound: 1-[2-(4-FLUOROPHENYL)ACETYL]-N~2~-[2-(2-PHENYL-1,3-THIAZOL-4-YL)ETHYL]-2-PYRROLIDINECARBOXAMIDE
Chemical Structure Depiction of ChemDiv screening compound L728-0211
1-[2-(4-FLUOROPHENYL)ACETYL]-N~2~-[2-(2-PHENYL-1,3-THIAZOL-4-YL)ETHYL]-2-PYRROLIDINECARBOXAMIDE
Available from 1 mg
Formats:
- Glass Vials (4ml Glass Vials VWR #97047-678)
- 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)
Shiptime: 1 week worldwide delivery in most cases
Compound Identifiers
ChemDiv Compound ID
L728-0211
Molecular Formula
C24H24FN3O2S (C24 H24 FN3 O2 S)
Compound Name
1-[2-(4-FLUOROPHENYL)ACETYL]-N~2~-[2-(2-PHENYL-1,3-THIAZOL-4-YL)ETHYL]-2-PYRROLIDINECARBOXAMIDE
IUPAC name
(2R)-1-[2-(4-fluorophenyl)acetyl]-N-[2-(2-phenyl-13-thiazol-4-yl)ethyl]pyrrolidine-2-carboxamide
SMILES
O=C(Cc(cc1)ccc1F)N(CCC1)C1C(NCCc1csc(-c2ccccc2)n1)=O
InChI Key
Chemical and Physical Properties
Saltdata
n/a
Molecular Weight
437.54
Hydrogen Bond Acceptors Count
5.00
Hydrogen Bond Donors Count
1.00
Rotatable Bond Count
9.00
Number of Nitrogen and Oxygen Atoms
5
Partition Coefficient, logP
3.738
Distribution Coefficient, logD
3.738
Water Solubility, LogSw
-4.00
Polar Surface Area
50.903
Acid Dissociation Constant (pKa)
14.30
Base Dissociation Constant (pKb)
1.76
Number of Chiral Centers
1.00
Percent sp3 carbon bonding
29.20
L728-0211 in Drug Discovery
Included in Screening Libraries
3D Mimetics PPI Library (1617 compounds)
Antiviral Library (67538 compounds)
GPCR Targeted Library (31838 compounds)
Macl-GPIb alpha Interaction Library (22969 compounds)
PI3K-Targeted Library (17255 compounds)
Protein-Protein Interaction Library (218420 compounds)
Serine Proteases Inhibitors Library (32732 compounds)
Targeted Diversity Library (40567 compounds)
Beyond the Flatland Library sp3 enriched (92988 compounds)
Epigenetics Focused Set (26518 compounds)
Peptidomimetic Library (37031 compounds)
Included in 1.7M Stock Database
- Mimetics
- 3D
- Cyclic compounds
- Mimetics
- Antiviral
- Infections
- Immune system
- Musculoskeletal
- Respiratory tract
- Nervous system
- Congenital
- Skin
- Metabolic
- Endocrine
- Hemic and lymphatic
- Cardiovascular
- Cancer
- Digestive system
- Respiratory tract
- Otorhinolaryngologic
- Male
- Female
- Hemic and lymphatic
- Skin
- Infections
- Cancer
- Musculoskeletal
- Digestive system
- Respiratory tract
- Male
- Female
- Cardiovascular
- Skin
- Metabolic
- Immune system
- GPCR
- Kinases
- Proteases
- Receptor's ligands
- PPI modulators
- PPI modulators
References: we are preparing a list of scientific research reports with L728-0211 chemical compound. It will be published here after verification.
Frequently Asked Questions
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Available from 1 mg in Glass Vials or 96-tube racks.
ChemDiv sends parcels with Express services (UPS, WC).
- 1–2 days for small orders
- 2–4 weeks for large selections
- 0.5–50 mg of dry powder sample in single glass vials, custom vials
- DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)