L728-0230 Screening compound: 1-(4-BROMOBENZOYL)-N-[2-(2-PHENYL-1,3-THIAZOL-4-YL)ETHYL]PROLINAMIDE

L728-0230 Screening compound: 1-(4-BROMOBENZOYL)-N-[2-(2-PHENYL-1,3-THIAZOL-4-YL)ETHYL]PROLINAMIDE
L728-0230 Screening compound: 1-(4-BROMOBENZOYL)-N-[2-(2-PHENYL-1,3-THIAZOL-4-YL)ETHYL]PROLINAMIDE alternative view

Chemical Structure Depiction of ChemDiv screening compound L728-0230
1-(4-BROMOBENZOYL)-N-[2-(2-PHENYL-1,3-THIAZOL-4-YL)ETHYL]PROLINAMIDE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L728-0230

Molecular Formula

C23H22BrN3O2S (C23 H22 BrN3 O2 S)

Compound Name

1-(4-BROMOBENZOYL)-N-[2-(2-PHENYL-1,3-THIAZOL-4-YL)ETHYL]PROLINAMIDE

IUPAC name

n/a

SMILES

O=C(C(CCC1)N1C(c(cc1)ccc1Br)=O)NCCc1csc(-c2ccccc2)n1

InChI

InChI=1S/C23H22BrN3O2S/c24-18-10-8-17(9-11-18)23(29)27-14-4-7-20(27)21(28)25-13-12-19-15-30-22(26-19)16-5-2-1-3-6-16/h1-3,5-6,8-11,15,20H,4,7,12-14H2,(H,25,28)/t20-/m0/s1

InChI Key

COIJQNFTUUPEBV-FQEVSTJZSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

484.42

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.437

Distribution Coefficient, logD

4.437

Water Solubility, LogSw

-4.32

Polar Surface Area

51.431

Acid Dissociation Constant (pKa)

14.53

Base Dissociation Constant (pKb)

1.76

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

26.10

L728-0230 in Drug Discovery

Included in Screening Libraries

3D Mimetics PPI Library (1617 compounds)

Antiviral Library (67538 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

PI3K-Targeted Library (17255 compounds)

Protein-Protein Interaction Library (218420 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Anti-HIV1 Library (19540 compounds)

Epigenetics Focused Set (26518 compounds)

New Agro Library (44492 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Structure:
  • Mimetics
  • 3D
  • Mimetics
Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Antiviral
  • Infections
  • Immune system
Targets:
  • Kinases
  • Proteases
Mechanism of action:
  • PPI modulators
  • PPI modulators
Agro:
  • Agro

References: we are preparing a list of scientific research reports with L728-0230 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L728-0230?
Check Price and Availability of L728-0230, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L728-0230 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L728-0230
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L728-0230
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L728-0230 available by request