L734-0269 Screening compound: 1-[2-(3-methylphenoxy)acetyl]-N-[2-(2-phenyl-1,3-thiazol-4-yl)ethyl]piperidine-4-carboxamide

L734-0269 Screening compound: 1-[2-(3-methylphenoxy)acetyl]-N-[2-(2-phenyl-1,3-thiazol-4-yl)ethyl]piperidine-4-carboxamide
L734-0269 Screening compound: 1-[2-(3-methylphenoxy)acetyl]-N-[2-(2-phenyl-1,3-thiazol-4-yl)ethyl]piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L734-0269
1-[2-(3-methylphenoxy)acetyl]-N-[2-(2-phenyl-1,3-thiazol-4-yl)ethyl]piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L734-0269

Molecular Formula

C26H29N3O3S (C26 H29 N3 O3 S)

Compound Name

1-[2-(3-methylphenoxy)acetyl]-N-[2-(2-phenyl-1,3-thiazol-4-yl)ethyl]piperidine-4-carboxamide

IUPAC name

1-[2-(3-methylphenoxy)acetyl]-N-[2-(2-phenyl-13-thiazol-4-yl)ethyl]piperidine-4-carboxamide

SMILES

Cc1cccc(OCC(N(CC2)CCC2C(NCCc2csc(-c3ccccc3)n2)=O)=O)c1

InChI

InChI=1S/C26H29N3O3S/c1-19-6-5-9-23(16-19)32-17-24(30)29-14-11-20(12-15-29)25(31)27-13-10-22-18-33-26(28-22)21-7-3-2-4-8-21/h2-9,16,18,20H,10-15,17H2,1H3,(H,27,31)

InChI Key

IUQNWCJQQCYKEG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15134206

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

463.6

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.765

Distribution Coefficient, logD

3.765

Water Solubility, LogSw

-3.80

Polar Surface Area

58.343

Acid Dissociation Constant (pKa)

14.27

Base Dissociation Constant (pKb)

1.76

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

34.60

L734-0269 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

GPCR Targeted Library (31838 compounds)

KRAS-Targeted Library (16000 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Protein-Protein Interaction Library (218420 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Hemic and lymphatic
  • Cardiovascular
  • Immune system
Targets:
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L734-0269 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L734-0269?
Check Price and Availability of L734-0269, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L734-0269 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L734-0269
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L734-0269
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L734-0269 available by request