L734-0276 Screening compound: 1-pentanoyl-N-[2-(2-phenyl-1,3-thiazol-4-yl)ethyl]piperidine-4-carboxamide

L734-0276 Screening compound: 1-pentanoyl-N-[2-(2-phenyl-1,3-thiazol-4-yl)ethyl]piperidine-4-carboxamide
L734-0276 Screening compound: 1-pentanoyl-N-[2-(2-phenyl-1,3-thiazol-4-yl)ethyl]piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L734-0276
1-pentanoyl-N-[2-(2-phenyl-1,3-thiazol-4-yl)ethyl]piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L734-0276

Molecular Formula

C22H29N3O2S (C22 H29 N3 O2 S)

Compound Name

1-pentanoyl-N-[2-(2-phenyl-1,3-thiazol-4-yl)ethyl]piperidine-4-carboxamide

IUPAC name

1-pentanoyl-N-[2-(2-phenyl-13-thiazol-4-yl)ethyl]piperidine-4-carboxamide

SMILES

CCCCC(N(CC1)CCC1C(NCCc1csc(-c2ccccc2)n1)=O)=O

InChI

InChI=1S/C22H29N3O2S/c1-2-3-9-20(26)25-14-11-17(12-15-25)21(27)23-13-10-19-16-28-22(24-19)18-7-5-4-6-8-18/h4-8,16-17H,2-3,9-15H2,1H3,(H,23,27)

InChI Key

CQYPTEWGEZUOTG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15134207

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

399.56

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.505

Distribution Coefficient, logD

3.505

Water Solubility, LogSw

-3.50

Polar Surface Area

51.115

Acid Dissociation Constant (pKa)

14.27

Base Dissociation Constant (pKb)

1.76

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

L734-0276 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L734-0276 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L734-0276?
Check Price and Availability of L734-0276, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L734-0276 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L734-0276
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L734-0276
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L734-0276 available by request