L734-0287 Screening compound: 1-(2-phenoxyacetyl)-N-[2-(2-phenyl-1,3-thiazol-4-yl)ethyl]piperidine-4-carboxamide

L734-0287 Screening compound: 1-(2-phenoxyacetyl)-N-[2-(2-phenyl-1,3-thiazol-4-yl)ethyl]piperidine-4-carboxamide
L734-0287 Screening compound: 1-(2-phenoxyacetyl)-N-[2-(2-phenyl-1,3-thiazol-4-yl)ethyl]piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L734-0287
1-(2-phenoxyacetyl)-N-[2-(2-phenyl-1,3-thiazol-4-yl)ethyl]piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L734-0287

Molecular Formula

C25H27N3O3S (C25 H27 N3 O3 S)

Compound Name

1-(2-phenoxyacetyl)-N-[2-(2-phenyl-1,3-thiazol-4-yl)ethyl]piperidine-4-carboxamide

IUPAC name

1-(2-phenoxyacetyl)-N-[2-(2-phenyl-13-thiazol-4-yl)ethyl]piperidine-4-carboxamide

SMILES

O=C(COc1ccccc1)N(CC1)CCC1C(NCCc1csc(-c2ccccc2)n1)=O

InChI

InChI=1S/C25H27N3O3S/c29-23(17-31-22-9-5-2-6-10-22)28-15-12-19(13-16-28)24(30)26-14-11-21-18-32-25(27-21)20-7-3-1-4-8-20/h1-10,18-19H,11-17H2,(H,26,30)

InChI Key

RYTMILVOHWVABR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15134208

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

449.57

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.245

Distribution Coefficient, logD

3.245

Water Solubility, LogSw

-3.24

Polar Surface Area

58.343

Acid Dissociation Constant (pKa)

14.27

Base Dissociation Constant (pKb)

1.76

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

32.00

L734-0287 in Drug Discovery

Included in Screening Libraries

Macl-GPIb alpha Interaction Library (22969 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
  • Immune system
Mechanism of action:
  • PPI modulators
  • Receptor's ligands
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L734-0287 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L734-0287?
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What is the minimum amount of L734-0287 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L734-0287
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L734-0287
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L734-0287 available by request