L735-0045 Screening compound: 1-[(5-chloro-2-thienyl)sulfonyl]-N~4~-[2-(2-methyl-1,3-thiazol-4-yl)ethyl]-4-piperidinecarboxamide

L735-0045 Screening compound: 1-[(5-chloro-2-thienyl)sulfonyl]-N~4~-[2-(2-methyl-1,3-thiazol-4-yl)ethyl]-4-piperidinecarboxamide
L735-0045 Screening compound: 1-[(5-chloro-2-thienyl)sulfonyl]-N~4~-[2-(2-methyl-1,3-thiazol-4-yl)ethyl]-4-piperidinecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L735-0045
1-[(5-chloro-2-thienyl)sulfonyl]-N~4~-[2-(2-methyl-1,3-thiazol-4-yl)ethyl]-4-piperidinecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L735-0045

Molecular Formula

C16H20ClN3O3S3 (C16 H20 ClN3 O3 S3)

Compound Name

1-[(5-chloro-2-thienyl)sulfonyl]-N~4~-[2-(2-methyl-1,3-thiazol-4-yl)ethyl]-4-piperidinecarboxamide

IUPAC name

n/a

SMILES

Cc1nc(CCNC(C(CC2)CCN2S(c(s2)ccc2Cl)(=O)=O)=O)cs1

InChI

InChI=1S/C16H20ClN3O3S3/c1-11-19-13(10-24-11)4-7-18-16(21)12-5-8-20(9-6-12)26(22,23)15-3-2-14(17)25-15/h2-3,10,12H,4-9H2,1H3,(H,18,21)

InChI Key

FXAWPOLPXWGIPE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15134274

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

434

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.631

Distribution Coefficient, logD

2.631

Water Solubility, LogSw

-3.47

Polar Surface Area

67.530

Acid Dissociation Constant (pKa)

14.27

Base Dissociation Constant (pKb)

3.63

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

L735-0045 in Drug Discovery

Included in Screening Libraries

Macl-GPIb alpha Interaction Library (22969 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L735-0045 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L735-0045?
Check Price and Availability of L735-0045, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L735-0045 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L735-0045
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L735-0045
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L735-0045 available by request