L735-0131 Screening compound: 1-(ethanesulfonyl)-N-{2-[2-(thiophen-2-yl)-1,3-thiazol-4-yl]ethyl}piperidine-4-carboxamide

L735-0131 Screening compound: 1-(ethanesulfonyl)-N-{2-[2-(thiophen-2-yl)-1,3-thiazol-4-yl]ethyl}piperidine-4-carboxamide
L735-0131 Screening compound: 1-(ethanesulfonyl)-N-{2-[2-(thiophen-2-yl)-1,3-thiazol-4-yl]ethyl}piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L735-0131
1-(ethanesulfonyl)-N-{2-[2-(thiophen-2-yl)-1,3-thiazol-4-yl]ethyl}piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L735-0131

Molecular Formula

C17H23N3O3S3 (C17 H23 N3 O3 S3)

Compound Name

1-(ethanesulfonyl)-N-{2-[2-(thiophen-2-yl)-1,3-thiazol-4-yl]ethyl}piperidine-4-carboxamide

IUPAC name

1-(ethanesulfonyl)-N-{2-[2-(thiophen-2-yl)-13-thiazol-4-yl]ethyl}piperidine-4-carboxamide

SMILES

CCS(N(CC1)CCC1C(NCCc1csc(-c2cccs2)n1)=O)(=O)=O

InChI

InChI=1S/C17H23N3O3S3/c1-2-26(22,23)20-9-6-13(7-10-20)16(21)18-8-5-14-12-25-17(19-14)15-4-3-11-24-15/h3-4,11-13H,2,5-10H2,1H3,(H,18,21)

InChI Key

XKQAPBAUWZVPEK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15134317

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

413.59

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.419

Distribution Coefficient, logD

2.419

Water Solubility, LogSw

-2.78

Polar Surface Area

67.618

Acid Dissociation Constant (pKa)

14.27

Base Dissociation Constant (pKb)

2.22

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

52.90

L735-0131 in Drug Discovery

Included in Screening Libraries

KRAS-Targeted Library (16000 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L735-0131 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L735-0131?
Check Price and Availability of L735-0131, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L735-0131 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L735-0131
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L735-0131
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L735-0131 available by request