L738-0008 Screening compound: N-[1-(3-chlorobenzoyl)piperidin-4-yl]-N-{[2-(thiophen-2-yl)-1,3-thiazol-4-yl]methyl}methanesulfonamide

L738-0008 Screening compound: N-[1-(3-chlorobenzoyl)piperidin-4-yl]-N-{[2-(thiophen-2-yl)-1,3-thiazol-4-yl]methyl}methanesulfonamide
L738-0008 Screening compound: N-[1-(3-chlorobenzoyl)piperidin-4-yl]-N-{[2-(thiophen-2-yl)-1,3-thiazol-4-yl]methyl}methanesulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L738-0008
N-[1-(3-chlorobenzoyl)piperidin-4-yl]-N-{[2-(thiophen-2-yl)-1,3-thiazol-4-yl]methyl}methanesulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L738-0008

Molecular Formula

C21H22ClN3O3S3 (C21 H22 ClN3 O3 S3)

Compound Name

N-[1-(3-chlorobenzoyl)piperidin-4-yl]-N-{[2-(thiophen-2-yl)-1,3-thiazol-4-yl]methyl}methanesulfonamide

IUPAC name

N-[1-(3-chlorobenzoyl)piperidin-4-yl]-N-{[2-(thiophen-2-yl)-13-thiazol-4-yl]methyl}methanesulfonamide

SMILES

CS(N(Cc1csc(-c2cccs2)n1)C(CC1)CCN1C(c1cccc(Cl)c1)=O)(=O)=O

InChI

InChI=1S/C21H22ClN3O3S3/c1-31(27,28)25(13-17-14-30-20(23-17)19-6-3-11-29-19)18-7-9-24(10-8-18)21(26)15-4-2-5-16(22)12-15/h2-6,11-12,14,18H,7-10,13H2,1H3

InChI Key

BXWBHRVCDRYKLX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15134331

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

496.07

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.375

Distribution Coefficient, logD

4.375

Water Solubility, LogSw

-4.52

Polar Surface Area

59.093

Acid Dissociation Constant (pKa)

24.48

Base Dissociation Constant (pKb)

3.38

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

L738-0008 in Drug Discovery

Included in Screening Libraries

MCL1 Targeted Library (12200 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic

References: we are preparing a list of scientific research reports with L738-0008 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L738-0008?
Check Price and Availability of L738-0008, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L738-0008 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L738-0008
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L738-0008
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L738-0008 available by request