L740-0440 Screening compound: N-(4-chlorophenyl)-4-[2-({3-[cyclohexyl(methyl)amino]propyl}amino)-2-oxoethyl]-3-oxotetrahydro-1(2H)-pyrazinecarboxamide

L740-0440 Screening compound: N-(4-chlorophenyl)-4-[2-({3-[cyclohexyl(methyl)amino]propyl}amino)-2-oxoethyl]-3-oxotetrahydro-1(2H)-pyrazinecarboxamide
L740-0440 Screening compound: N-(4-chlorophenyl)-4-[2-({3-[cyclohexyl(methyl)amino]propyl}amino)-2-oxoethyl]-3-oxotetrahydro-1(2H)-pyrazinecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L740-0440
N-(4-chlorophenyl)-4-[2-({3-[cyclohexyl(methyl)amino]propyl}amino)-2-oxoethyl]-3-oxotetrahydro-1(2H)-pyrazinecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L740-0440

Molecular Formula

C23H34ClN5O3 (C23 H34 ClN5 O3)

Compound Name

N-(4-chlorophenyl)-4-[2-({3-[cyclohexyl(methyl)amino]propyl}amino)-2-oxoethyl]-3-oxotetrahydro-1(2H)-pyrazinecarboxamide

IUPAC name

N-(4-chlorophenyl)-4-[({3-[cyclohexyl(methyl)amino]propyl}carbamoyl)methyl]-3-oxopiperazine-1-carboxamide

SMILES

CN(CCCNC(CN(CCN(C1)C(Nc(cc2)ccc2Cl)=O)C1=O)=O)C1CCCCC1

InChI

InChI=1S/C23H34ClN5O3/c1-27(20-6-3-2-4-7-20)13-5-12-25-21(30)16-28-14-15-29(17-22(28)31)23(32)26-19-10-8-18(24)9-11-19/h8-11,20H,2-7,12-17H2,1H3,(H,25,30)(H,26,32)

InChI Key

VHRQAFOWXRYPDX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27473383

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

464.01

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.009

Distribution Coefficient, logD

-0.574

Water Solubility, LogSw

-2.84

Polar Surface Area

69.696

Acid Dissociation Constant (pKa)

12.24

Base Dissociation Constant (pKb)

9.98

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

60.87

L740-0440 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

Protein-Protein Interaction Library (218420 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Mechanism of action:
  • PPI modulators
  • Receptor's ligands
Therapeutical areas:
  • Immune system

References: we are preparing a list of scientific research reports with L740-0440 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L740-0440?
Check Price and Availability of L740-0440, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L740-0440 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L740-0440
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L740-0440
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L740-0440 available by request