L740-0669 Screening compound: 4-{2-[(2,4-dimethoxybenzyl)amino]-2-oxoethyl}-N~1~-(4-fluorophenyl)-3-oxotetrahydro-1(2H)-pyrazinecarboxamide

L740-0669 Screening compound: 4-{2-[(2,4-dimethoxybenzyl)amino]-2-oxoethyl}-N~1~-(4-fluorophenyl)-3-oxotetrahydro-1(2H)-pyrazinecarboxamide
L740-0669 Screening compound: 4-{2-[(2,4-dimethoxybenzyl)amino]-2-oxoethyl}-N~1~-(4-fluorophenyl)-3-oxotetrahydro-1(2H)-pyrazinecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L740-0669
4-{2-[(2,4-dimethoxybenzyl)amino]-2-oxoethyl}-N~1~-(4-fluorophenyl)-3-oxotetrahydro-1(2H)-pyrazinecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L740-0669

Molecular Formula

C22H25FN4O5 (C22 H25 FN4 O5)

Compound Name

4-{2-[(2,4-dimethoxybenzyl)amino]-2-oxoethyl}-N~1~-(4-fluorophenyl)-3-oxotetrahydro-1(2H)-pyrazinecarboxamide

IUPAC name

n/a

SMILES

COc1cc(OC)c(CNC(CN(CCN(C2)C(Nc(cc3)ccc3F)=O)C2=O)=O)cc1

InChI

InChI=1S/C22H25FN4O5/c1-31-18-8-3-15(19(11-18)32-2)12-24-20(28)13-26-9-10-27(14-21(26)29)22(30)25-17-6-4-16(23)5-7-17/h3-8,11H,9-10,12-14H2,1-2H3,(H,24,28)(H,25,30)

InChI Key

KJEHHTNTDRMEOG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27473414

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

444.46

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.772

Distribution Coefficient, logD

1.772

Water Solubility, LogSw

-2.51

Polar Surface Area

81.991

Acid Dissociation Constant (pKa)

12.24

Base Dissociation Constant (pKb)

0.17

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.80

L740-0669 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • Receptor's ligands
Structure:
  • Cyclic compounds
Therapeutical areas:
  • Immune system

References: we are preparing a list of scientific research reports with L740-0669 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L740-0669?
Check Price and Availability of L740-0669, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L740-0669 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L740-0669
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L740-0669
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L740-0669 available by request