L740-0714 Screening compound: N-(4-bromophenyl)-4-[2-(3-fluoroanilino)-2-oxoethyl]-3-oxotetrahydro-1(2H)-pyrazinecarboxamide

L740-0714 Screening compound: N-(4-bromophenyl)-4-[2-(3-fluoroanilino)-2-oxoethyl]-3-oxotetrahydro-1(2H)-pyrazinecarboxamide
L740-0714 Screening compound: N-(4-bromophenyl)-4-[2-(3-fluoroanilino)-2-oxoethyl]-3-oxotetrahydro-1(2H)-pyrazinecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L740-0714
N-(4-bromophenyl)-4-[2-(3-fluoroanilino)-2-oxoethyl]-3-oxotetrahydro-1(2H)-pyrazinecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L740-0714

Molecular Formula

C19H18BrFN4O3 (C19 H18 BrFN4 O3)

Compound Name

N-(4-bromophenyl)-4-[2-(3-fluoroanilino)-2-oxoethyl]-3-oxotetrahydro-1(2H)-pyrazinecarboxamide

IUPAC name

N-(4-bromophenyl)-4-{[(3-fluorophenyl)carbamoyl]methyl}-3-oxopiperazine-1-carboxamide

SMILES

O=C(CN(CCN(C1)C(Nc(cc2)ccc2Br)=O)C1=O)Nc1cc(F)ccc1

InChI

InChI=1S/C19H18BrFN4O3/c20-13-4-6-15(7-5-13)23-19(28)25-9-8-24(18(27)12-25)11-17(26)22-16-3-1-2-14(21)10-16/h1-7,10H,8-9,11-12H2,(H,22,26)(H,23,28)

InChI Key

XTZCILLRQXDVQM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27473433

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

449.28

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.933

Distribution Coefficient, logD

2.932

Water Solubility, LogSw

-3.25

Polar Surface Area

65.494

Acid Dissociation Constant (pKa)

10.67

Base Dissociation Constant (pKb)

2.01

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.05

L740-0714 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Immunological Library (6760 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L740-0714 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L740-0714?
Check Price and Availability of L740-0714, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L740-0714 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L740-0714
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L740-0714
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L740-0714 available by request