L740-0749 Screening compound: 2-[3-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]-7-methyl-4-oxo-1,8-naphthyridin-1(4H)-yl]-N-[3-(methylthio)phenyl]acetamide

L740-0749 Screening compound: 2-[3-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]-7-methyl-4-oxo-1,8-naphthyridin-1(4H)-yl]-N-[3-(methylthio)phenyl]acetamide
L740-0749 Screening compound: 2-[3-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]-7-methyl-4-oxo-1,8-naphthyridin-1(4H)-yl]-N-[3-(methylthio)phenyl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L740-0749
2-[3-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]-7-methyl-4-oxo-1,8-naphthyridin-1(4H)-yl]-N-[3-(methylthio)phenyl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L740-0749

Molecular Formula

C20H28BrN5O3 (C20 H28 BrN5 O3)

Compound Name

2-[3-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]-7-methyl-4-oxo-1,8-naphthyridin-1(4H)-yl]-N-[3-(methylthio)phenyl]acetamide

IUPAC name

N-(4-bromophenyl)-3-oxo-4-[2-oxo-2-(4-propylpiperazin-1-yl)ethyl]piperazine-1-carboxamide

SMILES

CCCN(CC1)CCN1C(CN(CCN(C1)C(Nc(cc2)ccc2Br)=O)C1=O)=O

InChI

InChI=1S/C20H28BrN5O3/c1-2-7-23-8-10-24(11-9-23)18(27)14-25-12-13-26(15-19(25)28)20(29)22-17-5-3-16(21)4-6-17/h3-6H,2,7-15H2,1H3,(H,22,29)

InChI Key

BEFNTHZYDJJACR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27473446

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

466.38

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.359

Distribution Coefficient, logD

1.176

Water Solubility, LogSw

-2.21

Polar Surface Area

62.528

Acid Dissociation Constant (pKa)

12.24

Base Dissociation Constant (pKb)

7.12

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

55.00

L740-0749 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with L740-0749 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L740-0749?
Check Price and Availability of L740-0749, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L740-0749 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L740-0749
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L740-0749
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L740-0749 available by request