L741-0410 Screening compound: N-[2-(4-chlorophenyl)ethyl]-1-(4-fluorophenyl)-5-(pyridin-4-yl)-1H-1,2,3-triazole-4-carboxamide

L741-0410 Screening compound: N-[2-(4-chlorophenyl)ethyl]-1-(4-fluorophenyl)-5-(pyridin-4-yl)-1H-1,2,3-triazole-4-carboxamide
L741-0410 Screening compound: N-[2-(4-chlorophenyl)ethyl]-1-(4-fluorophenyl)-5-(pyridin-4-yl)-1H-1,2,3-triazole-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L741-0410
N-[2-(4-chlorophenyl)ethyl]-1-(4-fluorophenyl)-5-(pyridin-4-yl)-1H-1,2,3-triazole-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L741-0410

Molecular Formula

C22H17ClFN5O (C22 H17 ClFN5 O)

Compound Name

N-[2-(4-chlorophenyl)ethyl]-1-(4-fluorophenyl)-5-(pyridin-4-yl)-1H-1,2,3-triazole-4-carboxamide

IUPAC name

N-[2-(4-chlorophenyl)ethyl]-1-(4-fluorophenyl)-5-(pyridin-4-yl)-1H-123-triazole-4-carboxamide

SMILES

O=C(c1c(-c2ccncc2)n(-c(cc2)ccc2F)nn1)NCCc(cc1)ccc1Cl

InChI

InChI=1S/C22H17ClFN5O/c23-17-3-1-15(2-4-17)9-14-26-22(30)20-21(16-10-12-25-13-11-16)29(28-27-20)19-7-5-18(24)6-8-19/h1-8,10-13H,9,14H2,(H,26,30)

InChI Key

HHQGFTOHKPJBPY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27473515

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

421.86

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.220

Distribution Coefficient, logD

3.220

Water Solubility, LogSw

-3.78

Polar Surface Area

59.522

Acid Dissociation Constant (pKa)

14.62

Base Dissociation Constant (pKb)

3.27

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

9.10

L741-0410 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

SH2 Library (10483 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Endocrine
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with L741-0410 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L741-0410?
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What is the minimum amount of L741-0410 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L741-0410
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L741-0410
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L741-0410 available by request