L741-0421 Screening compound: 4-[1-(4-fluorophenyl)-5-(pyridin-4-yl)-1H-1,2,3-triazole-4-carbonyl]thiomorpholine

L741-0421 Screening compound: 4-[1-(4-fluorophenyl)-5-(pyridin-4-yl)-1H-1,2,3-triazole-4-carbonyl]thiomorpholine
L741-0421 Screening compound: 4-[1-(4-fluorophenyl)-5-(pyridin-4-yl)-1H-1,2,3-triazole-4-carbonyl]thiomorpholine alternative view

Chemical Structure Depiction of ChemDiv screening compound L741-0421
4-[1-(4-fluorophenyl)-5-(pyridin-4-yl)-1H-1,2,3-triazole-4-carbonyl]thiomorpholine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L741-0421

Molecular Formula

C18H16FN5OS (C18 H16 FN5 OS)

Compound Name

4-[1-(4-fluorophenyl)-5-(pyridin-4-yl)-1H-1,2,3-triazole-4-carbonyl]thiomorpholine

IUPAC name

4-[1-(4-fluorophenyl)-5-(pyridin-4-yl)-1H-123-triazole-4-carbonyl]thiomorpholine

SMILES

O=C(c1c(-c2ccncc2)n(-c(cc2)ccc2F)nn1)N1CCSCC1

InChI

InChI=1S/C18H16FN5OS/c19-14-1-3-15(4-2-14)24-17(13-5-7-20-8-6-13)16(21-22-24)18(25)23-9-11-26-12-10-23/h1-8H,9-12H2

InChI Key

SQZPZABNDXQTCM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD16638620

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

369.42

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

1.676

Distribution Coefficient, logD

1.676

Water Solubility, LogSw

-1.79

Polar Surface Area

51.916

Acid Dissociation Constant (pKa)

28.22

Base Dissociation Constant (pKb)

3.27

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.20

L741-0421 in Drug Discovery

Included in Screening Libraries

SH2 Library (10483 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Endocrine
  • Nervous system
  • Cardiovascular
Mechanism of action:
  • PPI modulators
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with L741-0421 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L741-0421?
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What is the minimum amount of L741-0421 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L741-0421
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L741-0421
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L741-0421 available by request