L741-3188 Screening compound: 1-(2-methylphenyl)-5-(pyridin-4-yl)-N-{[4-(trifluoromethyl)phenyl]methyl}-1H-1,2,3-triazole-4-carboxamide

L741-3188 Screening compound: 1-(2-methylphenyl)-5-(pyridin-4-yl)-N-{[4-(trifluoromethyl)phenyl]methyl}-1H-1,2,3-triazole-4-carboxamide
L741-3188 Screening compound: 1-(2-methylphenyl)-5-(pyridin-4-yl)-N-{[4-(trifluoromethyl)phenyl]methyl}-1H-1,2,3-triazole-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L741-3188
1-(2-methylphenyl)-5-(pyridin-4-yl)-N-{[4-(trifluoromethyl)phenyl]methyl}-1H-1,2,3-triazole-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L741-3188

Molecular Formula

C23H18F3N5O (C23 H18 F3 N5 O)

Compound Name

1-(2-methylphenyl)-5-(pyridin-4-yl)-N-{[4-(trifluoromethyl)phenyl]methyl}-1H-1,2,3-triazole-4-carboxamide

IUPAC name

1-(2-methylphenyl)-5-(pyridin-4-yl)-N-{[4-(trifluoromethyl)phenyl]methyl}-1H-123-triazole-4-carboxamide

SMILES

Cc(cccc1)c1-n1nnc(C(NCc2ccc(C(F)(F)F)cc2)=O)c1-c1ccncc1

InChI

InChI=1S/C23H18F3N5O/c1-15-4-2-3-5-19(15)31-21(17-10-12-27-13-11-17)20(29-30-31)22(32)28-14-16-6-8-18(9-7-16)23(24,25)26/h2-13H,14H2,1H3,(H,28,32)

InChI Key

DXPWVOKNKIXSBU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27473652

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

437.42

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.920

Distribution Coefficient, logD

3.920

Water Solubility, LogSw

-3.91

Polar Surface Area

59.380

Acid Dissociation Constant (pKa)

13.25

Base Dissociation Constant (pKb)

3.27

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.00

L741-3188 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

MCL1 Targeted Library (12200 compounds)

SH2 Library (10483 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Cancer
  • Endocrine
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with L741-3188 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L741-3188?
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What is the minimum amount of L741-3188 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L741-3188
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L741-3188
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L741-3188 available by request