L748-0180 Screening compound: 1-(3-fluoro-4-methylphenyl)-3-{2-[5-(piperidine-1-carbonyl)-1H-1,3-benzodiazol-1-yl]ethyl}urea
Chemical Structure Depiction of ChemDiv screening compound L748-0180
1-(3-fluoro-4-methylphenyl)-3-{2-[5-(piperidine-1-carbonyl)-1H-1,3-benzodiazol-1-yl]ethyl}urea
Available from 1 mg
Formats:
- Glass Vials (4ml Glass Vials VWR #97047-678)
- 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)
Shiptime: 1 week worldwide delivery in most cases
Compound Identifiers
ChemDiv Compound ID
L748-0180
Molecular Formula
C23H26FN5O2 (C23 H26 FN5 O2)
Compound Name
1-(3-fluoro-4-methylphenyl)-3-{2-[5-(piperidine-1-carbonyl)-1H-1,3-benzodiazol-1-yl]ethyl}urea
IUPAC name
1-(3-fluoro-4-methylphenyl)-3-{2-[5-(piperidine-1-carbonyl)-1H-13-benzodiazol-1-yl]ethyl}urea
SMILES
Cc(ccc(NC(NCCn1c(ccc(C(N2CCCCC2)=O)c2)c2nc1)=O)c1)c1F
InChI Key
MDL Number (MFCD)
Chemical and Physical Properties
Saltdata
n/a
Molecular Weight
423.49
Hydrogen Bond Acceptors Count
5.00
Hydrogen Bond Donors Count
2.00
Rotatable Bond Count
8.00
Number of Nitrogen and Oxygen Atoms
7
Partition Coefficient, logP
3.029
Distribution Coefficient, logD
3.027
Water Solubility, LogSw
-3.18
Polar Surface Area
60.788
Acid Dissociation Constant (pKa)
11.45
Base Dissociation Constant (pKb)
5.16
Number of Chiral Centers
0.00
Percent sp3 carbon bonding
34.80
L748-0180 in Drug Discovery
Included in Screening Libraries
Lipid Metabolism Library (9174 compounds)
Epigenetics Focused Set (26518 compounds)
Peptidomimetic Library (37031 compounds)
Included in 1.7M Stock Database
- Cardiovascular
- Metabolic
- PPI modulators
- Mimetics
References: we are preparing a list of scientific research reports with L748-0180 chemical compound. It will be published here after verification.
Frequently Asked Questions
Check Price and Availability of L748-0180, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
Available from 1 mg in Glass Vials or 96-tube racks.
ChemDiv sends parcels with Express services (UPS, WC).
- 1–2 days for small orders
- 2–4 weeks for large selections
- 0.5–50 mg of dry powder sample in single glass vials, custom vials
- DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)