L766-0404 Screening compound: N-{5-[(4-methylphenyl)sulfonyl]-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl}-2-pyrazinecarboxamide

L766-0404 Screening compound: N-{5-[(4-methylphenyl)sulfonyl]-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl}-2-pyrazinecarboxamide
L766-0404 Screening compound: N-{5-[(4-methylphenyl)sulfonyl]-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl}-2-pyrazinecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L766-0404
N-{5-[(4-methylphenyl)sulfonyl]-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl}-2-pyrazinecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L766-0404

Molecular Formula

C18H17N5O3S2 (C18 H17 N5 O3 S2)

Compound Name

N-{5-[(4-methylphenyl)sulfonyl]-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl}-2-pyrazinecarboxamide

IUPAC name

N-[5-(4-methylbenzenesulfonyl)-4H5H6H7H-[13]thiazolo[54-c]pyridin-2-yl]pyrazine-2-carboxamide

SMILES

Cc(cc1)ccc1S(N(CC1)Cc2c1nc(NC(c1nccnc1)=O)s2)(=O)=O

InChI

InChI=1S/C18H17N5O3S2/c1-12-2-4-13(5-3-12)28(25,26)23-9-6-14-16(11-23)27-18(21-14)22-17(24)15-10-19-7-8-20-15/h2-5,7-8,10H,6,9,11H2,1H3,(H,21,22,24)

InChI Key

HZOMULNNOTUKGW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27473961

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

415.5

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.478

Distribution Coefficient, logD

0.685

Water Solubility, LogSw

-2.75

Polar Surface Area

84.815

Acid Dissociation Constant (pKa)

5.61

Base Dissociation Constant (pKb)

0.12

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.22

L766-0404 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L766-0404 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L766-0404?
Check Price and Availability of L766-0404, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L766-0404 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L766-0404
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L766-0404
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L766-0404 available by request