L766-0421 Screening compound: 4-ethoxy-N-[5-(4-methylbenzenesulfonyl)-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl]benzamide

L766-0421 Screening compound: 4-ethoxy-N-[5-(4-methylbenzenesulfonyl)-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl]benzamide
L766-0421 Screening compound: 4-ethoxy-N-[5-(4-methylbenzenesulfonyl)-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl]benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L766-0421
4-ethoxy-N-[5-(4-methylbenzenesulfonyl)-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl]benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L766-0421

Molecular Formula

C22H23N3O4S2 (C22 H23 N3 O4 S2)

Compound Name

4-ethoxy-N-[5-(4-methylbenzenesulfonyl)-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl]benzamide

IUPAC name

4-ethoxy-N-[5-(4-methylbenzenesulfonyl)-4H5H6H7H-[13]thiazolo[54-c]pyridin-2-yl]benzamide

SMILES

CCOc(cc1)ccc1C(Nc1nc(CCN(C2)S(c3ccc(C)cc3)(=O)=O)c2s1)=O

InChI

InChI=1S/C22H23N3O4S2/c1-3-29-17-8-6-16(7-9-17)21(26)24-22-23-19-12-13-25(14-20(19)30-22)31(27,28)18-10-4-15(2)5-11-18/h4-11H,3,12-14H2,1-2H3,(H,23,24,26)

InChI Key

OMBFNKGEPOYYKC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27473973

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

457.57

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.560

Distribution Coefficient, logD

3.521

Water Solubility, LogSw

-4.13

Polar Surface Area

73.373

Acid Dissociation Constant (pKa)

6.40

Base Dissociation Constant (pKb)

0.25

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.30

L766-0421 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with L766-0421 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L766-0421?
Check Price and Availability of L766-0421, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L766-0421 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L766-0421
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L766-0421
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L766-0421 available by request