L766-0491 Screening compound: N-{5-[(4-methylphenyl)sulfonyl]-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl}propanamide

L766-0491 Screening compound: N-{5-[(4-methylphenyl)sulfonyl]-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl}propanamide
L766-0491 Screening compound: N-{5-[(4-methylphenyl)sulfonyl]-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl}propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L766-0491
N-{5-[(4-methylphenyl)sulfonyl]-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl}propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L766-0491

Molecular Formula

C16H19N3O3S2 (C16 H19 N3 O3 S2)

Compound Name

N-{5-[(4-methylphenyl)sulfonyl]-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl}propanamide

IUPAC name

N-[5-(4-methylbenzenesulfonyl)-4H5H6H7H-[13]thiazolo[54-c]pyridin-2-yl]propanamide

SMILES

CCC(Nc1nc(CCN(C2)S(c3ccc(C)cc3)(=O)=O)c2s1)=O

InChI

InChI=1S/C16H19N3O3S2/c1-3-15(20)18-16-17-13-8-9-19(10-14(13)23-16)24(21,22)12-6-4-11(2)5-7-12/h4-7H,3,8-10H2,1-2H3,(H,17,18,20)

InChI Key

YNWYUERTICAGHX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27474003

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

365.48

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.970

Distribution Coefficient, logD

2.760

Water Solubility, LogSw

-3.43

Polar Surface Area

66.308

Acid Dissociation Constant (pKa)

7.61

Base Dissociation Constant (pKb)

0.29

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

37.50

L766-0491 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L766-0491 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L766-0491?
Check Price and Availability of L766-0491, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L766-0491 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L766-0491
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L766-0491
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L766-0491 available by request