L766-0504 Screening compound: 3-chloro-4-fluoro-N-[5-(4-methylbenzenesulfonyl)-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl]benzamide

L766-0504 Screening compound: 3-chloro-4-fluoro-N-[5-(4-methylbenzenesulfonyl)-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl]benzamide
L766-0504 Screening compound: 3-chloro-4-fluoro-N-[5-(4-methylbenzenesulfonyl)-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl]benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L766-0504
3-chloro-4-fluoro-N-[5-(4-methylbenzenesulfonyl)-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl]benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L766-0504

Molecular Formula

C20H17ClFN3O3S2 (C20 H17 ClFN3 O3 S2)

Compound Name

3-chloro-4-fluoro-N-[5-(4-methylbenzenesulfonyl)-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl]benzamide

IUPAC name

3-chloro-4-fluoro-N-[5-(4-methylbenzenesulfonyl)-4H5H6H7H-[13]thiazolo[54-c]pyridin-2-yl]benzamide

SMILES

Cc(cc1)ccc1S(N(CC1)Cc2c1nc(NC(c(cc1)cc(Cl)c1F)=O)s2)(=O)=O

InChI

InChI=1S/C20H17ClFN3O3S2/c1-12-2-5-14(6-3-12)30(27,28)25-9-8-17-18(11-25)29-20(23-17)24-19(26)13-4-7-16(22)15(21)10-13/h2-7,10H,8-9,11H2,1H3,(H,23,24,26)

InChI Key

OUROWXUTAXGUKJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27474012

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

465.96

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.731

Distribution Coefficient, logD

1.592

Water Solubility, LogSw

-4.86

Polar Surface Area

66.250

Acid Dissociation Constant (pKa)

4.26

Base Dissociation Constant (pKb)

0.25

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

L766-0504 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Peptidomimetic Library (37031 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics
Therapeutical areas:
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L766-0504 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L766-0504?
Check Price and Availability of L766-0504, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L766-0504 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L766-0504
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L766-0504
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L766-0504 available by request