L766-0554 Screening compound: N-[5-(benzenesulfonyl)-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl]-3,5-dimethoxybenzamide

L766-0554 Screening compound: N-[5-(benzenesulfonyl)-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl]-3,5-dimethoxybenzamide
L766-0554 Screening compound: N-[5-(benzenesulfonyl)-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl]-3,5-dimethoxybenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L766-0554
N-[5-(benzenesulfonyl)-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl]-3,5-dimethoxybenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L766-0554

Molecular Formula

C21H21N3O5S2 (C21 H21 N3 O5 S2)

Compound Name

N-[5-(benzenesulfonyl)-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl]-3,5-dimethoxybenzamide

IUPAC name

N-[5-(benzenesulfonyl)-4H5H6H7H-[13]thiazolo[54-c]pyridin-2-yl]-35-dimethoxybenzamide

SMILES

COc1cc(C(Nc2nc(CCN(C3)S(c4ccccc4)(=O)=O)c3s2)=O)cc(OC)c1

InChI

InChI=1S/C21H21N3O5S2/c1-28-15-10-14(11-16(12-15)29-2)20(25)23-21-22-18-8-9-24(13-19(18)30-21)31(26,27)17-6-4-3-5-7-17/h3-7,10-12H,8-9,13H2,1-2H3,(H,22,23,25)

InChI Key

CJMDRFGDCNFUPC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27474027

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

459.55

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.848

Distribution Coefficient, logD

3.502

Water Solubility, LogSw

-4.08

Polar Surface Area

81.337

Acid Dissociation Constant (pKa)

7.31

Base Dissociation Constant (pKb)

0.25

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.80

L766-0554 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with L766-0554 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L766-0554?
Check Price and Availability of L766-0554, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L766-0554 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L766-0554
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L766-0554
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L766-0554 available by request