L766-0578 Screening compound: N-[5-(benzenesulfonyl)-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl]-4-bromobenzamide

L766-0578 Screening compound: N-[5-(benzenesulfonyl)-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl]-4-bromobenzamide
L766-0578 Screening compound: N-[5-(benzenesulfonyl)-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl]-4-bromobenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L766-0578
N-[5-(benzenesulfonyl)-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl]-4-bromobenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L766-0578

Molecular Formula

C19H16BrN3O3S2 (C19 H16 BrN3 O3 S2)

Compound Name

N-[5-(benzenesulfonyl)-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl]-4-bromobenzamide

IUPAC name

N-[5-(benzenesulfonyl)-4H5H6H7H-[13]thiazolo[54-c]pyridin-2-yl]-4-bromobenzamide

SMILES

O=C(c(cc1)ccc1Br)Nc1nc(CCN(C2)S(c3ccccc3)(=O)=O)c2s1

InChI

InChI=1S/C19H16BrN3O3S2/c20-14-8-6-13(7-9-14)18(24)22-19-21-16-10-11-23(12-17(16)27-19)28(25,26)15-4-2-1-3-5-15/h1-9H,10-12H2,(H,21,22,24)

InChI Key

VMQCASAKDGCQJX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27474032

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

478.39

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.417

Distribution Coefficient, logD

2.174

Water Solubility, LogSw

-4.34

Polar Surface Area

66.250

Acid Dissociation Constant (pKa)

5.16

Base Dissociation Constant (pKb)

0.25

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

15.80

L766-0578 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Anti-infective Library (19449 compounds)

Peptidomimetic Library (37031 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Infections
  • Immune system
  • animal
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Kinases
  • Kinases
Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with L766-0578 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L766-0578?
Check Price and Availability of L766-0578, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L766-0578 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L766-0578
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L766-0578
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L766-0578 available by request