L766-0718 Screening compound: 4-(dimethylamino)-N-[5-(4-methoxybenzenesulfonyl)-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl]benzamide

L766-0718 Screening compound: 4-(dimethylamino)-N-[5-(4-methoxybenzenesulfonyl)-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl]benzamide
L766-0718 Screening compound: 4-(dimethylamino)-N-[5-(4-methoxybenzenesulfonyl)-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl]benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L766-0718
4-(dimethylamino)-N-[5-(4-methoxybenzenesulfonyl)-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl]benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L766-0718

Molecular Formula

C22H24N4O4S2 (C22 H24 N4 O4 S2)

Compound Name

4-(dimethylamino)-N-[5-(4-methoxybenzenesulfonyl)-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl]benzamide

IUPAC name

4-(dimethylamino)-N-[5-(4-methoxybenzenesulfonyl)-4H5H6H7H-[13]thiazolo[54-c]pyridin-2-yl]benzamide

SMILES

CN(C)c(cc1)ccc1C(Nc1nc(CCN(C2)S(c(cc3)ccc3OC)(=O)=O)c2s1)=O

InChI

InChI=1S/C22H24N4O4S2/c1-25(2)16-6-4-15(5-7-16)21(27)24-22-23-19-12-13-26(14-20(19)31-22)32(28,29)18-10-8-17(30-3)9-11-18/h4-11H,12-14H2,1-3H3,(H,23,24,27)

InChI Key

WPGVGVBHWVATPQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27474059

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

472.59

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.840

Distribution Coefficient, logD

2.326

Water Solubility, LogSw

-4.06

Polar Surface Area

76.598

Acid Dissociation Constant (pKa)

5.90

Base Dissociation Constant (pKb)

8.18

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.30

L766-0718 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with L766-0718 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L766-0718?
Check Price and Availability of L766-0718, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L766-0718 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L766-0718
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L766-0718
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L766-0718 available by request