L767-0255 Screening compound: 1-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-[5-(4-methylbenzenesulfonyl)-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl]urea

L767-0255 Screening compound: 1-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-[5-(4-methylbenzenesulfonyl)-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl]urea
L767-0255 Screening compound: 1-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-[5-(4-methylbenzenesulfonyl)-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl]urea alternative view

Chemical Structure Depiction of ChemDiv screening compound L767-0255
1-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-[5-(4-methylbenzenesulfonyl)-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl]urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L767-0255

Molecular Formula

C22H22N4O5S2 (C22 H22 N4 O5 S2)

Compound Name

1-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-[5-(4-methylbenzenesulfonyl)-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl]urea

IUPAC name

1-(23-dihydro-14-benzodioxin-6-yl)-3-[5-(4-methylbenzenesulfonyl)-4H5H6H7H-[13]thiazolo[54-c]pyridin-2-yl]urea

SMILES

Cc(cc1)ccc1S(N(CC1)Cc2c1nc(NC(Nc(cc1)cc3c1OCCO3)=O)s2)(=O)=O

InChI

InChI=1S/C22H22N4O5S2/c1-14-2-5-16(6-3-14)33(28,29)26-9-8-17-20(13-26)32-22(24-17)25-21(27)23-15-4-7-18-19(12-15)31-11-10-30-18/h2-7,12H,8-11,13H2,1H3,(H2,23,24,25,27)

InChI Key

QAZOEDWOAQSTDW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27474096

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

486.57

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.651

Distribution Coefficient, logD

3.635

Water Solubility, LogSw

-3.79

Polar Surface Area

91.285

Acid Dissociation Constant (pKa)

8.82

Base Dissociation Constant (pKb)

1.83

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.30

L767-0255 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with L767-0255 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L767-0255?
Check Price and Availability of L767-0255, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L767-0255 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L767-0255
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L767-0255
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L767-0255 available by request