L767-0444 Screening compound: 1-(4-ethoxyphenyl)-3-[5-(4-methoxybenzenesulfonyl)-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl]urea

L767-0444 Screening compound: 1-(4-ethoxyphenyl)-3-[5-(4-methoxybenzenesulfonyl)-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl]urea
L767-0444 Screening compound: 1-(4-ethoxyphenyl)-3-[5-(4-methoxybenzenesulfonyl)-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl]urea alternative view

Chemical Structure Depiction of ChemDiv screening compound L767-0444
1-(4-ethoxyphenyl)-3-[5-(4-methoxybenzenesulfonyl)-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl]urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L767-0444

Molecular Formula

C22H24N4O5S2 (C22 H24 N4 O5 S2)

Compound Name

1-(4-ethoxyphenyl)-3-[5-(4-methoxybenzenesulfonyl)-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl]urea

IUPAC name

1-(4-ethoxyphenyl)-3-[5-(4-methoxybenzenesulfonyl)-4H5H6H7H-[13]thiazolo[54-c]pyridin-2-yl]urea

SMILES

CCOc(cc1)ccc1NC(Nc1nc(CCN(C2)S(c(cc3)ccc3OC)(=O)=O)c2s1)=O

InChI

InChI=1S/C22H24N4O5S2/c1-3-31-17-6-4-15(5-7-17)23-21(27)25-22-24-19-12-13-26(14-20(19)32-22)33(28,29)18-10-8-16(30-2)9-11-18/h4-11H,3,12-14H2,1-2H3,(H2,23,24,25,27)

InChI Key

JIKJCAOIQPPNCB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27474134

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

488.59

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

4.607

Distribution Coefficient, logD

4.575

Water Solubility, LogSw

-4.16

Polar Surface Area

90.129

Acid Dissociation Constant (pKa)

8.52

Base Dissociation Constant (pKb)

1.83

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.30

L767-0444 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Anticancer Library (62698 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with L767-0444 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L767-0444?
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What is the minimum amount of L767-0444 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L767-0444
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L767-0444
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L767-0444 available by request