L767-0445 Screening compound: 1-(2,3-dimethylphenyl)-3-[5-(4-methoxybenzenesulfonyl)-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl]urea

L767-0445 Screening compound: 1-(2,3-dimethylphenyl)-3-[5-(4-methoxybenzenesulfonyl)-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl]urea
L767-0445 Screening compound: 1-(2,3-dimethylphenyl)-3-[5-(4-methoxybenzenesulfonyl)-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl]urea alternative view

Chemical Structure Depiction of ChemDiv screening compound L767-0445
1-(2,3-dimethylphenyl)-3-[5-(4-methoxybenzenesulfonyl)-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl]urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L767-0445

Molecular Formula

C22H24N4O4S2 (C22 H24 N4 O4 S2)

Compound Name

1-(2,3-dimethylphenyl)-3-[5-(4-methoxybenzenesulfonyl)-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridin-2-yl]urea

IUPAC name

1-(23-dimethylphenyl)-3-[5-(4-methoxybenzenesulfonyl)-4H5H6H7H-[13]thiazolo[54-c]pyridin-2-yl]urea

SMILES

Cc1cccc(NC(Nc2nc(CCN(C3)S(c(cc4)ccc4OC)(=O)=O)c3s2)=O)c1C

InChI

InChI=1S/C22H24N4O4S2/c1-14-5-4-6-18(15(14)2)23-21(27)25-22-24-19-11-12-26(13-20(19)31-22)32(28,29)17-9-7-16(30-3)8-10-17/h4-10H,11-13H2,1-3H3,(H2,23,24,25,27)

InChI Key

JBTLRXUZSZNZGB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27474135

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

472.59

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.869

Distribution Coefficient, logD

4.848

Water Solubility, LogSw

-4.41

Polar Surface Area

82.307

Acid Dissociation Constant (pKa)

8.70

Base Dissociation Constant (pKb)

1.83

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.30

L767-0445 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with L767-0445 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L767-0445?
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What is the minimum amount of L767-0445 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L767-0445
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L767-0445
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L767-0445 available by request