L774-0547 Screening compound: (3-{[(4-chlorobenzyl)oxy]methyl}-1-methyl-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl)(3,5-dimethoxyphenyl)methanone

L774-0547 Screening compound: (3-{[(4-chlorobenzyl)oxy]methyl}-1-methyl-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl)(3,5-dimethoxyphenyl)methanone
L774-0547 Screening compound: (3-{[(4-chlorobenzyl)oxy]methyl}-1-methyl-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl)(3,5-dimethoxyphenyl)methanone alternative view

Chemical Structure Depiction of ChemDiv screening compound L774-0547
(3-{[(4-chlorobenzyl)oxy]methyl}-1-methyl-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl)(3,5-dimethoxyphenyl)methanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L774-0547

Molecular Formula

C24H26ClN3O4 (C24 H26 ClN3 O4)

Compound Name

(3-{[(4-chlorobenzyl)oxy]methyl}-1-methyl-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl)(3,5-dimethoxyphenyl)methanone

IUPAC name

3-{[(4-chlorophenyl)methoxy]methyl}-5-(35-dimethoxybenzoyl)-1-methyl-1H4H5H6H7H-pyrazolo[43-c]pyridine

SMILES

Cn1nc(COCc(cc2)ccc2Cl)c(C2)c1CCN2C(c1cc(OC)cc(OC)c1)=O

InChI

InChI=1S/C24H26ClN3O4/c1-27-23-8-9-28(24(29)17-10-19(30-2)12-20(11-17)31-3)13-21(23)22(26-27)15-32-14-16-4-6-18(25)7-5-16/h4-7,10-12H,8-9,13-15H2,1-3H3

InChI Key

SAQAAQVKQJJAOR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27474195

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

455.94

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.276

Distribution Coefficient, logD

3.276

Water Solubility, LogSw

-3.75

Polar Surface Area

55.312

Acid Dissociation Constant (pKa)

21.95

Base Dissociation Constant (pKb)

12.18

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.33

L774-0547 in Drug Discovery

Included in Screening Libraries

Cysteine Proteases Inhibitors Library (7839 compounds)

Hsp90-Targeted Library (11355 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Anti-HIV1 Library (19540 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Nervous system
  • Cardiovascular
  • Skin
  • Metabolic
  • Endocrine
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Antiviral
  • Infections
  • Immune system
Targets:
  • Proteases
  • Kinases

References: we are preparing a list of scientific research reports with L774-0547 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L774-0547?
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What is the minimum amount of L774-0547 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L774-0547
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L774-0547
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L774-0547 available by request