L774-0659 Screening compound: 1-(3-{[(4-chlorobenzyl)oxy]methyl}-1-methyl-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl)-1-ethanone

L774-0659 Screening compound: 1-(3-{[(4-chlorobenzyl)oxy]methyl}-1-methyl-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl)-1-ethanone
L774-0659 Screening compound: 1-(3-{[(4-chlorobenzyl)oxy]methyl}-1-methyl-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl)-1-ethanone alternative view

Chemical Structure Depiction of ChemDiv screening compound L774-0659
1-(3-{[(4-chlorobenzyl)oxy]methyl}-1-methyl-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl)-1-ethanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L774-0659

Molecular Formula

C17H20ClN3O2 (C17 H20 ClN3 O2)

Compound Name

1-(3-{[(4-chlorobenzyl)oxy]methyl}-1-methyl-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl)-1-ethanone

IUPAC name

1-(3-{[(4-chlorophenyl)methoxy]methyl}-1-methyl-1H4H5H6H7H-pyrazolo[43-c]pyridin-5-yl)ethan-1-one

SMILES

CC(N(CC1)Cc2c1n(C)nc2COCc(cc1)ccc1Cl)=O

InChI

InChI=1S/C17H20ClN3O2/c1-12(22)21-8-7-17-15(9-21)16(19-20(17)2)11-23-10-13-3-5-14(18)6-4-13/h3-6H,7-11H2,1-2H3

InChI Key

DHBRWSCXGBPXCN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27474202

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

333.82

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

1.821

Distribution Coefficient, logD

1.821

Water Solubility, LogSw

-2.61

Polar Surface Area

40.964

Acid Dissociation Constant (pKa)

22.95

Base Dissociation Constant (pKb)

9.89

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

41.18

L774-0659 in Drug Discovery

Included in Screening Libraries

Cysteine Proteases Inhibitors Library (7839 compounds)

Eccentric PPI Library (11937 compounds)

Hsp90-Targeted Library (11355 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Nervous system
  • Cardiovascular
  • Skin
  • Metabolic
  • Endocrine
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Proteases
  • Kinases
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L774-0659 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L774-0659?
Check Price and Availability of L774-0659, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L774-0659 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L774-0659
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L774-0659
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L774-0659 available by request