L775-0352 Screening compound: 3-{[(2-chloro-4-fluorophenyl)methoxy]methyl}-N-(3-methoxyphenyl)-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-5-carboxamide

L775-0352 Screening compound: 3-{[(2-chloro-4-fluorophenyl)methoxy]methyl}-N-(3-methoxyphenyl)-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-5-carboxamide
L775-0352 Screening compound: 3-{[(2-chloro-4-fluorophenyl)methoxy]methyl}-N-(3-methoxyphenyl)-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L775-0352
3-{[(2-chloro-4-fluorophenyl)methoxy]methyl}-N-(3-methoxyphenyl)-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L775-0352

Molecular Formula

C23H24ClFN4O3 (C23 H24 ClFN4 O3)

Compound Name

3-{[(2-chloro-4-fluorophenyl)methoxy]methyl}-N-(3-methoxyphenyl)-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-5-carboxamide

IUPAC name

3-{[(2-chloro-4-fluorophenyl)methoxy]methyl}-N-(3-methoxyphenyl)-1-methyl-1H4H5H6H7H-pyrazolo[43-c]pyridine-5-carboxamide

SMILES

Cn1nc(COCc(ccc(F)c2)c2Cl)c(C2)c1CCN2C(Nc1cc(OC)ccc1)=O

InChI

InChI=1S/C23H24ClFN4O3/c1-28-22-8-9-29(23(30)26-17-4-3-5-18(11-17)31-2)12-19(22)21(27-28)14-32-13-15-6-7-16(25)10-20(15)24/h3-7,10-11H,8-9,12-14H2,1-2H3,(H,26,30)

InChI Key

QXJLKIHDMXILRI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27474286

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

458.92

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.806

Distribution Coefficient, logD

3.806

Water Solubility, LogSw

-4.27

Polar Surface Area

56.589

Acid Dissociation Constant (pKa)

13.09

Base Dissociation Constant (pKb)

8.23

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.40

L775-0352 in Drug Discovery

Included in Screening Libraries

Cysteine Proteases Inhibitors Library (7839 compounds)

Hsp90-Targeted Library (11355 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Nervous system
  • Cardiovascular
  • Skin
  • Metabolic
  • Endocrine
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with L775-0352 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L775-0352?
Check Price and Availability of L775-0352, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L775-0352 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L775-0352
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L775-0352
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L775-0352 available by request