L775-0674 Screening compound: N-(2,4-dimethylphenyl)-3-{[(3-fluorophenyl)methoxy]methyl}-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-5-carboxamide

L775-0674 Screening compound: N-(2,4-dimethylphenyl)-3-{[(3-fluorophenyl)methoxy]methyl}-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-5-carboxamide
L775-0674 Screening compound: N-(2,4-dimethylphenyl)-3-{[(3-fluorophenyl)methoxy]methyl}-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L775-0674
N-(2,4-dimethylphenyl)-3-{[(3-fluorophenyl)methoxy]methyl}-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L775-0674

Molecular Formula

C24H27FN4O2 (C24 H27 FN4 O2)

Compound Name

N-(2,4-dimethylphenyl)-3-{[(3-fluorophenyl)methoxy]methyl}-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-5-carboxamide

IUPAC name

N-(24-dimethylphenyl)-3-{[(3-fluorophenyl)methoxy]methyl}-1-methyl-1H4H5H6H7H-pyrazolo[43-c]pyridine-5-carboxamide

SMILES

Cc(cc1)cc(C)c1NC(N(CC1)Cc2c1n(C)nc2COCc1cccc(F)c1)=O

InChI

InChI=1S/C24H27FN4O2/c1-16-7-8-21(17(2)11-16)26-24(30)29-10-9-23-20(13-29)22(27-28(23)3)15-31-14-18-5-4-6-19(25)12-18/h4-8,11-12H,9-10,13-15H2,1-3H3,(H,26,30)

InChI Key

LJGFSPHIPSWYJI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27474378

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

422.5

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.914

Distribution Coefficient, logD

3.914

Water Solubility, LogSw

-3.96

Polar Surface Area

48.347

Acid Dissociation Constant (pKa)

13.71

Base Dissociation Constant (pKb)

2.65

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

L775-0674 in Drug Discovery

Included in Screening Libraries

Cysteine Proteases Inhibitors Library (7839 compounds)

Eccentric PPI Library (11937 compounds)

Hsp90-Targeted Library (11355 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Nervous system
  • Cardiovascular
  • Skin
  • Metabolic
  • Endocrine
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
Targets:
  • Proteases
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L775-0674 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L775-0674?
Check Price and Availability of L775-0674, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L775-0674 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L775-0674
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L775-0674
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L775-0674 available by request