L775-0725 Screening compound: N~5~-(5-chloro-2-methoxyphenyl)-1-methyl-3-(phenoxymethyl)-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxamide

L775-0725 Screening compound: N~5~-(5-chloro-2-methoxyphenyl)-1-methyl-3-(phenoxymethyl)-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxamide
L775-0725 Screening compound: N~5~-(5-chloro-2-methoxyphenyl)-1-methyl-3-(phenoxymethyl)-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L775-0725
N~5~-(5-chloro-2-methoxyphenyl)-1-methyl-3-(phenoxymethyl)-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L775-0725

Molecular Formula

C22H23ClN4O3 (C22 H23 ClN4 O3)

Compound Name

N~5~-(5-chloro-2-methoxyphenyl)-1-methyl-3-(phenoxymethyl)-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxamide

IUPAC name

N-(5-chloro-2-methoxyphenyl)-1-methyl-3-(phenoxymethyl)-1H4H5H6H7H-pyrazolo[43-c]pyridine-5-carboxamide

SMILES

Cn1nc(COc2ccccc2)c(C2)c1CCN2C(Nc(cc(cc1)Cl)c1OC)=O

InChI

InChI=1S/C22H23ClN4O3/c1-26-20-10-11-27(22(28)24-18-12-15(23)8-9-21(18)29-2)13-17(20)19(25-26)14-30-16-6-4-3-5-7-16/h3-9,12H,10-11,13-14H2,1-2H3,(H,24,28)

InChI Key

GVWADNDZLZGKSC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27474392

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

426.9

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.508

Distribution Coefficient, logD

3.508

Water Solubility, LogSw

-3.95

Polar Surface Area

55.043

Acid Dissociation Constant (pKa)

10.74

Base Dissociation Constant (pKb)

8.46

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.27

L775-0725 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Cysteine Proteases Inhibitors Library (7839 compounds)

Hsp90-Targeted Library (11355 compounds)

Ligand-Gated Ion Channels Library (3887 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Nervous system
  • Cardiovascular
  • Skin
  • Metabolic
  • Endocrine
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Nervous system
  • Eye
Targets:
  • Proteases
  • Ion Channels

References: we are preparing a list of scientific research reports with L775-0725 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L775-0725?
Check Price and Availability of L775-0725, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L775-0725 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L775-0725
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L775-0725
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L775-0725 available by request