L775-0999 Screening compound: N~5~-(2,4-dimethylphenyl)-3-[(3-fluorophenoxy)methyl]-1-methyl-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxamide

L775-0999 Screening compound: N~5~-(2,4-dimethylphenyl)-3-[(3-fluorophenoxy)methyl]-1-methyl-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxamide
L775-0999 Screening compound: N~5~-(2,4-dimethylphenyl)-3-[(3-fluorophenoxy)methyl]-1-methyl-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L775-0999
N~5~-(2,4-dimethylphenyl)-3-[(3-fluorophenoxy)methyl]-1-methyl-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L775-0999

Molecular Formula

C23H25FN4O2 (C23 H25 FN4 O2)

Compound Name

N~5~-(2,4-dimethylphenyl)-3-[(3-fluorophenoxy)methyl]-1-methyl-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxamide

IUPAC name

n/a

SMILES

Cc(cc1)cc(C)c1NC(N(CC1)Cc2c1n(C)nc2COc1cccc(F)c1)=O

InChI

InChI=1S/C23H25FN4O2/c1-15-7-8-20(16(2)11-15)25-23(29)28-10-9-22-19(13-28)21(26-27(22)3)14-30-18-6-4-5-17(24)12-18/h4-8,11-12H,9-10,13-14H2,1-3H3,(H,25,29)

InChI Key

RHBRMBVAKGVLQE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27474453

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

408.48

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.876

Distribution Coefficient, logD

3.876

Water Solubility, LogSw

-3.99

Polar Surface Area

47.412

Acid Dissociation Constant (pKa)

13.71

Base Dissociation Constant (pKb)

7.88

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.43

L775-0999 in Drug Discovery

Included in Screening Libraries

Cysteine Proteases Inhibitors Library (7839 compounds)

Hsp90-Targeted Library (11355 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Nervous system
  • Cardiovascular
  • Skin
  • Metabolic
  • Endocrine
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
Targets:
  • Proteases
Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L775-0999 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L775-0999?
Check Price and Availability of L775-0999, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L775-0999 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L775-0999
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L775-0999
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L775-0999 available by request