L776-0721 Screening compound: 3-{[(2-chloro-4-fluorophenyl)methoxy]methyl}-5-(3,5-dimethylbenzenesulfonyl)-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine

L776-0721 Screening compound: 3-{[(2-chloro-4-fluorophenyl)methoxy]methyl}-5-(3,5-dimethylbenzenesulfonyl)-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine
L776-0721 Screening compound: 3-{[(2-chloro-4-fluorophenyl)methoxy]methyl}-5-(3,5-dimethylbenzenesulfonyl)-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine alternative view

Chemical Structure Depiction of ChemDiv screening compound L776-0721
3-{[(2-chloro-4-fluorophenyl)methoxy]methyl}-5-(3,5-dimethylbenzenesulfonyl)-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L776-0721

Molecular Formula

C23H25ClFN3O3S (C23 H25 ClFN3 O3 S)

Compound Name

3-{[(2-chloro-4-fluorophenyl)methoxy]methyl}-5-(3,5-dimethylbenzenesulfonyl)-1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine

IUPAC name

3-{[(2-chloro-4-fluorophenyl)methoxy]methyl}-5-(35-dimethylbenzenesulfonyl)-1-methyl-1H4H5H6H7H-pyrazolo[43-c]pyridine

SMILES

Cc1cc(S(N(CC2)Cc3c2n(C)nc3COCc(ccc(F)c2)c2Cl)(=O)=O)cc(C)c1

InChI

InChI=1S/C23H25ClFN3O3S/c1-15-8-16(2)10-19(9-15)32(29,30)28-7-6-23-20(12-28)22(26-27(23)3)14-31-13-17-4-5-18(25)11-21(17)24/h4-5,8-11H,6-7,12-14H2,1-3H3

InChI Key

WLZGOICSQBUHSG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27474561

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

477.99

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.509

Distribution Coefficient, logD

4.509

Water Solubility, LogSw

-4.54

Polar Surface Area

55.287

Acid Dissociation Constant (pKa)

22.23

Base Dissociation Constant (pKb)

-6.61

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

34.80

L776-0721 in Drug Discovery

Included in Screening Libraries

Antifungal Library (16415 compounds)

Cysteine Proteases Inhibitors Library (7839 compounds)

Hsp90-Targeted Library (11355 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Nervous system
  • Cardiovascular
  • Skin
  • Metabolic
  • Endocrine
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Agro:
  • Agro
Targets:
  • Proteases
  • Kinases

References: we are preparing a list of scientific research reports with L776-0721 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L776-0721?
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What is the minimum amount of L776-0721 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L776-0721
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L776-0721
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L776-0721 available by request