L794-0183 Screening compound: 1-(3-oxo-3,4-dihydro-2H-1,4-benzothiazine-2-carbonyl)-N-[4-(trifluoromethoxy)phenyl]piperidine-4-carboxamide

L794-0183 Screening compound: 1-(3-oxo-3,4-dihydro-2H-1,4-benzothiazine-2-carbonyl)-N-[4-(trifluoromethoxy)phenyl]piperidine-4-carboxamide
L794-0183 Screening compound: 1-(3-oxo-3,4-dihydro-2H-1,4-benzothiazine-2-carbonyl)-N-[4-(trifluoromethoxy)phenyl]piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L794-0183
1-(3-oxo-3,4-dihydro-2H-1,4-benzothiazine-2-carbonyl)-N-[4-(trifluoromethoxy)phenyl]piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L794-0183

Molecular Formula

C22H20F3N3O4S (C22 H20 F3 N3 O4 S)

Compound Name

1-(3-oxo-3,4-dihydro-2H-1,4-benzothiazine-2-carbonyl)-N-[4-(trifluoromethoxy)phenyl]piperidine-4-carboxamide

IUPAC name

1-(3-oxo-34-dihydro-2H-14-benzothiazine-2-carbonyl)-N-[4-(trifluoromethoxy)phenyl]piperidine-4-carboxamide

SMILES

O=C(C(CC1)CCN1C(C1Sc(cccc2)c2NC1=O)=O)Nc(cc1)ccc1OC(F)(F)F

InChI

InChI=1S/C22H20F3N3O4S/c23-22(24,25)32-15-7-5-14(6-8-15)26-19(29)13-9-11-28(12-10-13)21(31)18-20(30)27-16-3-1-2-4-17(16)33-18/h1-8,13,18H,9-12H2,(H,26,29)(H,27,30)/t18-/m1/s1

InChI Key

JSNKGRWADZUMCA-GOSISDBHSA-N

MDL Number (MFCD)

MFCD15134977

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

479.48

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.348

Distribution Coefficient, logD

3.347

Water Solubility, LogSw

-3.60

Polar Surface Area

70.792

Acid Dissociation Constant (pKa)

11.75

Base Dissociation Constant (pKb)

3.96

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

31.80

L794-0183 in Drug Discovery

Included in Screening Libraries

Macl-GPIb alpha Interaction Library (22969 compounds)

SmartTM Library (51161 compounds)

Anti-HIV1 Library (19540 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
  • Antiviral
  • Infections
  • Immune system

References: we are preparing a list of scientific research reports with L794-0183 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L794-0183?
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What is the minimum amount of L794-0183 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L794-0183
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L794-0183
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L794-0183 available by request