L800-0140 Screening compound: N~5~-(4-fluorobenzyl)-4-methyl-2-(2-oxo-1-pyrrolidinyl)-1,3-thiazole-5-carboxamide

L800-0140 Screening compound: N~5~-(4-fluorobenzyl)-4-methyl-2-(2-oxo-1-pyrrolidinyl)-1,3-thiazole-5-carboxamide
L800-0140 Screening compound: N~5~-(4-fluorobenzyl)-4-methyl-2-(2-oxo-1-pyrrolidinyl)-1,3-thiazole-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L800-0140
N~5~-(4-fluorobenzyl)-4-methyl-2-(2-oxo-1-pyrrolidinyl)-1,3-thiazole-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L800-0140

Molecular Formula

C16H16FN3O2S (C16 H16 FN3 O2 S)

Compound Name

N~5~-(4-fluorobenzyl)-4-methyl-2-(2-oxo-1-pyrrolidinyl)-1,3-thiazole-5-carboxamide

IUPAC name

N-[(4-fluorophenyl)methyl]-4-methyl-2-(2-oxopyrrolidin-1-yl)-13-thiazole-5-carboxamide

SMILES

Cc1c(C(NCc(cc2)ccc2F)=O)sc(N(CCC2)C2=O)n1

InChI

InChI=1S/C16H16FN3O2S/c1-10-14(23-16(19-10)20-8-2-3-13(20)21)15(22)18-9-11-4-6-12(17)7-5-11/h4-7H,2-3,8-9H2,1H3,(H,18,22)

InChI Key

ZJXKTNNHWOOAEF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27475909

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

333.39

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.660

Distribution Coefficient, logD

2.660

Water Solubility, LogSw

-3.04

Polar Surface Area

51.866

Acid Dissociation Constant (pKa)

11.44

Base Dissociation Constant (pKb)

-1.04

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.25

L800-0140 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

Antiparasite Library (23996 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Agro:
  • Agro
  • Agro
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L800-0140 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L800-0140?
Check Price and Availability of L800-0140, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L800-0140 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L800-0140
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L800-0140
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L800-0140 available by request