L814-0686 Screening compound: 3-chloro-2-methyl-N-(4-{[1,2,4]triazolo[4,3-a]quinoxalin-4-yloxy}phenyl)benzene-1-sulfonamide

L814-0686 Screening compound: 3-chloro-2-methyl-N-(4-{[1,2,4]triazolo[4,3-a]quinoxalin-4-yloxy}phenyl)benzene-1-sulfonamide
L814-0686 Screening compound: 3-chloro-2-methyl-N-(4-{[1,2,4]triazolo[4,3-a]quinoxalin-4-yloxy}phenyl)benzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L814-0686
3-chloro-2-methyl-N-(4-{[1,2,4]triazolo[4,3-a]quinoxalin-4-yloxy}phenyl)benzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L814-0686

Molecular Formula

C22H16ClN5O3S (C22 H16 ClN5 O3 S)

Compound Name

3-chloro-2-methyl-N-(4-{[1,2,4]triazolo[4,3-a]quinoxalin-4-yloxy}phenyl)benzene-1-sulfonamide

IUPAC name

3-chloro-2-methyl-N-(4-{[124]triazolo[43-a]quinoxalin-4-yloxy}phenyl)benzene-1-sulfonamide

SMILES

Cc(c(S(Nc(cc1)ccc1Oc1nc(cccc2)c2n2c1nnc2)(=O)=O)ccc1)c1Cl

InChI

InChI=1S/C22H16ClN5O3S/c1-14-17(23)5-4-8-20(14)32(29,30)27-15-9-11-16(12-10-15)31-22-21-26-24-13-28(21)19-7-3-2-6-18(19)25-22/h2-13,27H,1H3

InChI Key

VADANSNSZAOJPS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27476940

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

465.92

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.485

Distribution Coefficient, logD

4.380

Water Solubility, LogSw

-4.54

Polar Surface Area

78.681

Acid Dissociation Constant (pKa)

7.96

Base Dissociation Constant (pKb)

2.02

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

4.50

L814-0686 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L814-0686 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L814-0686?
Check Price and Availability of L814-0686, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L814-0686 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L814-0686
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L814-0686
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L814-0686 available by request