L814-0767 Screening compound: N-(3-{[1,2,4]triazolo[4,3-a]quinoxalin-4-yloxy}phenyl)thiophene-2-carboxamide

L814-0767 Screening compound: N-(3-{[1,2,4]triazolo[4,3-a]quinoxalin-4-yloxy}phenyl)thiophene-2-carboxamide
L814-0767 Screening compound: N-(3-{[1,2,4]triazolo[4,3-a]quinoxalin-4-yloxy}phenyl)thiophene-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L814-0767
N-(3-{[1,2,4]triazolo[4,3-a]quinoxalin-4-yloxy}phenyl)thiophene-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L814-0767

Molecular Formula

C20H13N5O2S (C20 H13 N5 O2 S)

Compound Name

N-(3-{[1,2,4]triazolo[4,3-a]quinoxalin-4-yloxy}phenyl)thiophene-2-carboxamide

IUPAC name

N-(3-{[124]triazolo[43-a]quinoxalin-4-yloxy}phenyl)thiophene-2-carboxamide

SMILES

O=C(c1cccs1)Nc1cc(Oc2nc(cccc3)c3n3c2nnc3)ccc1

InChI

InChI=1S/C20H13N5O2S/c26-19(17-9-4-10-28-17)22-13-5-3-6-14(11-13)27-20-18-24-21-12-25(18)16-8-2-1-7-15(16)23-20/h1-12H,(H,22,26)

InChI Key

QBHYCYJNMLFZDA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27476977

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

387.42

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.598

Distribution Coefficient, logD

3.598

Water Solubility, LogSw

-3.92

Polar Surface Area

62.141

Acid Dissociation Constant (pKa)

12.07

Base Dissociation Constant (pKb)

2.02

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

L814-0767 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L814-0767 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L814-0767?
Check Price and Availability of L814-0767, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L814-0767 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L814-0767
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L814-0767
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L814-0767 available by request