L821-1628 Screening compound: N-[(5-{5-[(pyridin-4-ylsulfanyl)methyl]-1,2,4-oxadiazol-3-yl}thiophen-2-yl)methyl]cyclopropanecarboxamide

L821-1628 Screening compound: N-[(5-{5-[(pyridin-4-ylsulfanyl)methyl]-1,2,4-oxadiazol-3-yl}thiophen-2-yl)methyl]cyclopropanecarboxamide
L821-1628 Screening compound: N-[(5-{5-[(pyridin-4-ylsulfanyl)methyl]-1,2,4-oxadiazol-3-yl}thiophen-2-yl)methyl]cyclopropanecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L821-1628
N-[(5-{5-[(pyridin-4-ylsulfanyl)methyl]-1,2,4-oxadiazol-3-yl}thiophen-2-yl)methyl]cyclopropanecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L821-1628

Molecular Formula

C17H16N4O2S2 (C17 H16 N4 O2 S2)

Compound Name

N-[(5-{5-[(pyridin-4-ylsulfanyl)methyl]-1,2,4-oxadiazol-3-yl}thiophen-2-yl)methyl]cyclopropanecarboxamide

IUPAC name

N-[(5-{5-[(pyridin-4-ylsulfanyl)methyl]-124-oxadiazol-3-yl}thiophen-2-yl)methyl]cyclopropanecarboxamide

SMILES

O=C(C1CC1)NCc1ccc(-c2noc(CSc3ccncc3)n2)s1

InChI

InChI=1S/C17H16N4O2S2/c22-17(11-1-2-11)19-9-13-3-4-14(25-13)16-20-15(23-21-16)10-24-12-5-7-18-8-6-12/h3-8,11H,1-2,9-10H2,(H,19,22)

InChI Key

FTTPAUZSUMHOTM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27477432

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

372.47

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.908

Distribution Coefficient, logD

2.793

Water Solubility, LogSw

-3.11

Polar Surface Area

66.693

Acid Dissociation Constant (pKa)

14.25

Base Dissociation Constant (pKb)

6.88

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.40

L821-1628 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Immunological Library (6760 compounds)

PD-1/L1 Library (498 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Immune system
  • Cancer
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
Targets:
  • GPCR
  • Others
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L821-1628 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L821-1628?
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What is the minimum amount of L821-1628 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L821-1628
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L821-1628
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L821-1628 available by request