L821-1681 Screening compound: N-[(5-{5-[1-(4-methoxyphenyl)cyclopropyl]-1,2,4-oxadiazol-3-yl}thiophen-2-yl)methyl]cyclopropanecarboxamide

L821-1681 Screening compound: N-[(5-{5-[1-(4-methoxyphenyl)cyclopropyl]-1,2,4-oxadiazol-3-yl}thiophen-2-yl)methyl]cyclopropanecarboxamide
L821-1681 Screening compound: N-[(5-{5-[1-(4-methoxyphenyl)cyclopropyl]-1,2,4-oxadiazol-3-yl}thiophen-2-yl)methyl]cyclopropanecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L821-1681
N-[(5-{5-[1-(4-methoxyphenyl)cyclopropyl]-1,2,4-oxadiazol-3-yl}thiophen-2-yl)methyl]cyclopropanecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L821-1681

Molecular Formula

C21H21N3O3S (C21 H21 N3 O3 S)

Compound Name

N-[(5-{5-[1-(4-methoxyphenyl)cyclopropyl]-1,2,4-oxadiazol-3-yl}thiophen-2-yl)methyl]cyclopropanecarboxamide

IUPAC name

N-[(5-{5-[1-(4-methoxyphenyl)cyclopropyl]-124-oxadiazol-3-yl}thiophen-2-yl)methyl]cyclopropanecarboxamide

SMILES

COc1ccc(C2(CC2)c2nc(-c3ccc(CNC(C4CC4)=O)s3)no2)cc1

InChI

InChI=1S/C21H21N3O3S/c1-26-15-6-4-14(5-7-15)21(10-11-21)20-23-18(24-27-20)17-9-8-16(28-17)12-22-19(25)13-2-3-13/h4-9,13H,2-3,10-12H2,1H3,(H,22,25)

InChI Key

SMZQWRHMXWITLI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27477467

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

395.48

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.191

Distribution Coefficient, logD

4.191

Water Solubility, LogSw

-4.23

Polar Surface Area

65.394

Acid Dissociation Constant (pKa)

14.25

Base Dissociation Constant (pKb)

-0.52

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.10

L821-1681 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

SmartTM Library (51161 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • PPI modulators

References: we are preparing a list of scientific research reports with L821-1681 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L821-1681?
Check Price and Availability of L821-1681, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L821-1681 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L821-1681
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L821-1681
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L821-1681 available by request