L823-0859 Screening compound: 4-(3-{5-[(4-phenylpiperazin-1-yl)sulfonyl]thiophen-3-yl}-1,2,4-oxadiazole-5-carbonyl)morpholine

L823-0859 Screening compound: 4-(3-{5-[(4-phenylpiperazin-1-yl)sulfonyl]thiophen-3-yl}-1,2,4-oxadiazole-5-carbonyl)morpholine
L823-0859 Screening compound: 4-(3-{5-[(4-phenylpiperazin-1-yl)sulfonyl]thiophen-3-yl}-1,2,4-oxadiazole-5-carbonyl)morpholine alternative view

Chemical Structure Depiction of ChemDiv screening compound L823-0859
4-(3-{5-[(4-phenylpiperazin-1-yl)sulfonyl]thiophen-3-yl}-1,2,4-oxadiazole-5-carbonyl)morpholine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L823-0859

Molecular Formula

C21H23N5O5S2 (C21 H23 N5 O5 S2)

Compound Name

4-(3-{5-[(4-phenylpiperazin-1-yl)sulfonyl]thiophen-3-yl}-1,2,4-oxadiazole-5-carbonyl)morpholine

IUPAC name

4-(3-{5-[(4-phenylpiperazin-1-yl)sulfonyl]thiophen-3-yl}-124-oxadiazole-5-carbonyl)morpholine

SMILES

O=C(c1nc(-c2csc(S(N(CC3)CCN3c3ccccc3)(=O)=O)c2)no1)N1CCOCC1

InChI

InChI=1S/C21H23N5O5S2/c27-21(25-10-12-30-13-11-25)20-22-19(23-31-20)16-14-18(32-15-16)33(28,29)26-8-6-24(7-9-26)17-4-2-1-3-5-17/h1-5,14-15H,6-13H2

InChI Key

HAKDUMSFBXSNNR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27477770

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

489.58

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

2.185

Distribution Coefficient, logD

2.185

Water Solubility, LogSw

-2.73

Polar Surface Area

92.462

Acid Dissociation Constant (pKa)

28.26

Base Dissociation Constant (pKb)

2.24

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.10

L823-0859 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L823-0859 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L823-0859?
Check Price and Availability of L823-0859, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L823-0859 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L823-0859
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L823-0859
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L823-0859 available by request