L824-0015 Screening compound: N-(5-chloropyridin-2-yl)-2-methyl-5-[5-(pyrrolidine-1-carbonyl)-1,2,4-oxadiazol-3-yl]thiophene-3-sulfonamide

L824-0015 Screening compound: N-(5-chloropyridin-2-yl)-2-methyl-5-[5-(pyrrolidine-1-carbonyl)-1,2,4-oxadiazol-3-yl]thiophene-3-sulfonamide
L824-0015 Screening compound: N-(5-chloropyridin-2-yl)-2-methyl-5-[5-(pyrrolidine-1-carbonyl)-1,2,4-oxadiazol-3-yl]thiophene-3-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L824-0015
N-(5-chloropyridin-2-yl)-2-methyl-5-[5-(pyrrolidine-1-carbonyl)-1,2,4-oxadiazol-3-yl]thiophene-3-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L824-0015

Molecular Formula

C17H16ClN5O4S2 (C17 H16 ClN5 O4 S2)

Compound Name

N-(5-chloropyridin-2-yl)-2-methyl-5-[5-(pyrrolidine-1-carbonyl)-1,2,4-oxadiazol-3-yl]thiophene-3-sulfonamide

IUPAC name

N-(5-chloropyridin-2-yl)-2-methyl-5-[5-(pyrrolidine-1-carbonyl)-124-oxadiazol-3-yl]thiophene-3-sulfonamide

SMILES

Cc(sc(-c1noc(C(N2CCCC2)=O)n1)c1)c1S(Nc(cc1)ncc1Cl)(=O)=O

InChI

InChI=1S/C17H16ClN5O4S2/c1-10-13(29(25,26)22-14-5-4-11(18)9-19-14)8-12(28-10)15-20-16(27-21-15)17(24)23-6-2-3-7-23/h4-5,8-9H,2-3,6-7H2,1H3,(H,19,22)

InChI Key

HJEODSCEDKSKIE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27477819

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

453.93

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.372

Distribution Coefficient, logD

1.810

Water Solubility, LogSw

-3.68

Polar Surface Area

100.303

Acid Dissociation Constant (pKa)

5.85

Base Dissociation Constant (pKb)

-0.55

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.40

L824-0015 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Immunological Library (6760 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Neuropeptide S Library (2850 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Digestive system
  • Nervous system
Targets:
  • GPCR
  • Kinases
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • Receptor's ligands
Agro:
  • Agro

References: we are preparing a list of scientific research reports with L824-0015 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L824-0015?
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What is the minimum amount of L824-0015 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L824-0015
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L824-0015
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L824-0015 available by request