L824-1021 Screening compound: 2-methyl-5-[5-(morpholine-4-carbonyl)-1,2,4-oxadiazol-3-yl]-N-(5,6,7,8-tetrahydronaphthalen-1-yl)thiophene-3-sulfonamide

L824-1021 Screening compound: 2-methyl-5-[5-(morpholine-4-carbonyl)-1,2,4-oxadiazol-3-yl]-N-(5,6,7,8-tetrahydronaphthalen-1-yl)thiophene-3-sulfonamide
L824-1021 Screening compound: 2-methyl-5-[5-(morpholine-4-carbonyl)-1,2,4-oxadiazol-3-yl]-N-(5,6,7,8-tetrahydronaphthalen-1-yl)thiophene-3-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L824-1021
2-methyl-5-[5-(morpholine-4-carbonyl)-1,2,4-oxadiazol-3-yl]-N-(5,6,7,8-tetrahydronaphthalen-1-yl)thiophene-3-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L824-1021

Molecular Formula

C22H24N4O5S2 (C22 H24 N4 O5 S2)

Compound Name

2-methyl-5-[5-(morpholine-4-carbonyl)-1,2,4-oxadiazol-3-yl]-N-(5,6,7,8-tetrahydronaphthalen-1-yl)thiophene-3-sulfonamide

IUPAC name

2-methyl-5-[5-(morpholine-4-carbonyl)-124-oxadiazol-3-yl]-N-(5678-tetrahydronaphthalen-1-yl)thiophene-3-sulfonamide

SMILES

Cc(sc(-c1noc(C(N2CCOCC2)=O)n1)c1)c1S(Nc1c(CCCC2)c2ccc1)(=O)=O

InChI

InChI=1S/C22H24N4O5S2/c1-14-19(33(28,29)25-17-8-4-6-15-5-2-3-7-16(15)17)13-18(32-14)20-23-21(31-24-20)22(27)26-9-11-30-12-10-26/h4,6,8,13,25H,2-3,5,7,9-12H2,1H3

InChI Key

ZUZLJRLQWRNYTF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27477953

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

488.59

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.685

Distribution Coefficient, logD

3.684

Water Solubility, LogSw

-3.89

Polar Surface Area

97.363

Acid Dissociation Constant (pKa)

9.96

Base Dissociation Constant (pKb)

-4.22

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.90

L824-1021 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L824-1021 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L824-1021?
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What is the minimum amount of L824-1021 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L824-1021
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L824-1021
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L824-1021 available by request