L827-0517 Screening compound: 1-{5-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-yl}-4-propylpiperazine

L827-0517 Screening compound: 1-{5-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-yl}-4-propylpiperazine
L827-0517 Screening compound: 1-{5-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-yl}-4-propylpiperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound L827-0517
1-{5-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-yl}-4-propylpiperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L827-0517

Molecular Formula

C21H25N5O (C21 H25 N5 O)

Compound Name

1-{5-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-yl}-4-propylpiperazine

IUPAC name

1-{5-[3-(4-methylphenyl)-124-oxadiazol-5-yl]pyridin-2-yl}-4-propylpiperazine

SMILES

CCCN(CC1)CCN1c(cc1)ncc1-c1nc(-c2ccc(C)cc2)no1

InChI

InChI=1S/C21H25N5O/c1-3-10-25-11-13-26(14-12-25)19-9-8-18(15-22-19)21-23-20(24-27-21)17-6-4-16(2)5-7-17/h4-9,15H,3,10-14H2,1-2H3

InChI Key

BAZBFHUKGPHICJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27478197

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

363.46

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.875

Distribution Coefficient, logD

4.173

Water Solubility, LogSw

-4.37

Polar Surface Area

47.488

Acid Dissociation Constant (pKa)

24.58

Base Dissociation Constant (pKb)

8.01

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.10

L827-0517 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

SmartTM Library (51161 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system

References: we are preparing a list of scientific research reports with L827-0517 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L827-0517?
Check Price and Availability of L827-0517, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L827-0517 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L827-0517
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L827-0517
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L827-0517 available by request