L827-0572 Screening compound: 4-[2-({5-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-yl}amino)ethyl]benzene-1-sulfonamide

L827-0572 Screening compound: 4-[2-({5-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-yl}amino)ethyl]benzene-1-sulfonamide
L827-0572 Screening compound: 4-[2-({5-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-yl}amino)ethyl]benzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L827-0572
4-[2-({5-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-yl}amino)ethyl]benzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L827-0572

Molecular Formula

C22H21N5O3S (C22 H21 N5 O3 S)

Compound Name

4-[2-({5-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-yl}amino)ethyl]benzene-1-sulfonamide

IUPAC name

4-[2-({5-[3-(4-methylphenyl)-124-oxadiazol-5-yl]pyridin-2-yl}amino)ethyl]benzene-1-sulfonamide

SMILES

Cc(cc1)ccc1-c1noc(-c(cc2)cnc2NCCc(cc2)ccc2S(N)(=O)=O)n1

InChI

InChI=1S/C22H21N5O3S/c1-15-2-6-17(7-3-15)21-26-22(30-27-21)18-8-11-20(25-14-18)24-13-12-16-4-9-19(10-5-16)31(23,28)29/h2-11,14H,12-13H2,1H3,(H,24,25)(H2,23,28,29)

InChI Key

BFGXSGFWUJGDHG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27478216

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

435.51

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.831

Distribution Coefficient, logD

3.820

Water Solubility, LogSw

-3.96

Polar Surface Area

102.028

Acid Dissociation Constant (pKa)

10.18

Base Dissociation Constant (pKb)

5.79

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.60

L827-0572 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

Anticancer Library (62698 compounds)

C-Met Library (15277 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Protein-Protein Interaction Library (218420 compounds)

Targeted Diversity Library (40567 compounds)

SH2 PTB Focused Library (6188 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases
  • Kinases
Mechanism of action:
  • Receptor's ligands
  • PPI modulators

References: we are preparing a list of scientific research reports with L827-0572 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L827-0572?
Check Price and Availability of L827-0572, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L827-0572 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L827-0572
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L827-0572
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L827-0572 available by request