L827-0872 Screening compound: 2-{5-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-yl}-1,2,3,4-tetrahydroisoquinoline

L827-0872 Screening compound: 2-{5-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-yl}-1,2,3,4-tetrahydroisoquinoline
L827-0872 Screening compound: 2-{5-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-yl}-1,2,3,4-tetrahydroisoquinoline alternative view

Chemical Structure Depiction of ChemDiv screening compound L827-0872
2-{5-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-yl}-1,2,3,4-tetrahydroisoquinoline

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L827-0872

Molecular Formula

C23H20N4O2 (C23 H20 N4 O2)

Compound Name

2-{5-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-yl}-1,2,3,4-tetrahydroisoquinoline

IUPAC name

2-{5-[3-(4-methoxyphenyl)-124-oxadiazol-5-yl]pyridin-2-yl}-1234-tetrahydroisoquinoline

SMILES

COc(cc1)ccc1-c1noc(-c(cc2)cnc2N(CC2)Cc3c2cccc3)n1

InChI

InChI=1S/C23H20N4O2/c1-28-20-9-6-17(7-10-20)22-25-23(29-26-22)18-8-11-21(24-14-18)27-13-12-16-4-2-3-5-19(16)15-27/h2-11,14H,12-13,15H2,1H3

InChI Key

NPEBGCLLEUGOBU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27478252

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

384.44

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.557

Distribution Coefficient, logD

5.508

Water Solubility, LogSw

-5.47

Polar Surface Area

50.903

Acid Dissociation Constant (pKa)

21.01

Base Dissociation Constant (pKb)

6.47

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

17.40

L827-0872 in Drug Discovery

Included in Screening Libraries

Akt-Targeted Library (14764 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Nervous system
  • Cardiovascular
Targets:
  • Kinases
  • Ion Channels

References: we are preparing a list of scientific research reports with L827-0872 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L827-0872?
Check Price and Availability of L827-0872, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L827-0872 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L827-0872
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L827-0872
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L827-0872 available by request