L827-1265 Screening compound: 2-{5-[3-(3-methylphenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-yl}-1,2,3,4-tetrahydroisoquinoline

L827-1265 Screening compound: 2-{5-[3-(3-methylphenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-yl}-1,2,3,4-tetrahydroisoquinoline
L827-1265 Screening compound: 2-{5-[3-(3-methylphenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-yl}-1,2,3,4-tetrahydroisoquinoline alternative view

Chemical Structure Depiction of ChemDiv screening compound L827-1265
2-{5-[3-(3-methylphenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-yl}-1,2,3,4-tetrahydroisoquinoline

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L827-1265

Molecular Formula

C23H20N4O (C23 H20 N4 O)

Compound Name

2-{5-[3-(3-methylphenyl)-1,2,4-oxadiazol-5-yl]pyridin-2-yl}-1,2,3,4-tetrahydroisoquinoline

IUPAC name

2-{5-[3-(3-methylphenyl)-124-oxadiazol-5-yl]pyridin-2-yl}-1234-tetrahydroisoquinoline

SMILES

Cc1cccc(-c2noc(-c(cc3)cnc3N(CC3)Cc4c3cccc4)n2)c1

InChI

InChI=1S/C23H20N4O/c1-16-5-4-8-18(13-16)22-25-23(28-26-22)19-9-10-21(24-14-19)27-12-11-17-6-2-3-7-20(17)15-27/h2-10,13-14H,11-12,15H2,1H3

InChI Key

INRZSZNHNUDMPS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27478298

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

368.44

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.944

Distribution Coefficient, logD

5.895

Water Solubility, LogSw

-5.62

Polar Surface Area

43.359

Acid Dissociation Constant (pKa)

21.01

Base Dissociation Constant (pKb)

6.47

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

17.40

L827-1265 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with L827-1265 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L827-1265?
Check Price and Availability of L827-1265, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L827-1265 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L827-1265
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L827-1265
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L827-1265 available by request